Department of Biochemistry, MNR Medical College, Sangareddy, MNR Nagar, Sangareddy, Telangana State, 502295, India.
Department of General Medicine, Malla Reddy Institute of Medical Sciences, Hyderabad, India.
Diabetes Metab Syndr. 2021 May-Jun;15(3):885-889. doi: 10.1016/j.dsx.2021.04.012. Epub 2021 Apr 15.
BACKGROUND & AIMS: Diabetes mellitus (DM) and thyroid disorders are the most common endocrine disorders in clinical practice. Unrecognized thyroid disorders have an adverse effect on metabolic functions. The aim of the study is to demonstrate the prevalence of thyroid disorders in individuals with diabetes mellitus.
A prospective observational study, conducted at Sree Sidhi Vinayaka Diabetic Center, between September 2013 to December 2019. A total of 5037 patients attended the outpatient clinic, among which 2470 met the inclusion criteria. All patients underwent a clinical and laboratory evaluation.
A total of 2321 individuals with diabetes had consented to be the part of the study, 102 had Type 1 diabetes mellitus (T1DM) and 2219 Type 2 diabetes mellitus (T2DM). The mean age was 48.4 ± 10.7, among which 1128 females and 1193 are males. 79.9% (1853) individuals with diabetes were euthyroid; 13.8% (321) subclinical hypothyroidism; 3.4% (79) clinical hypothyroidism, and 2.9% (68) were having hyperthyroidism. 14.1% of T2DM had subclinical hypothyroidism, in contrast, clinical hypothyroidism was common in T1DM (6.9%).
A high index of suspicion for thyroid dysfunction in diabetics should be considered to screen for thyroid function in them for early detection and effective management of both the conditions.
糖尿病（DM）和甲状腺疾病是临床实践中最常见的内分泌疾病。未被识别的甲状腺疾病会对代谢功能产生不良影响。本研究旨在展示糖尿病患者中甲状腺疾病的患病率。
这是一项于 2013 年 9 月至 2019 年 12 月在 Sree Sidhi Vinayaka 糖尿病中心进行的前瞻性观察研究。共有 5037 名患者就诊于门诊，其中 2470 名符合纳入标准。所有患者均接受了临床和实验室评估。
共有 2321 名糖尿病患者同意参与研究，其中 102 名患有 1 型糖尿病（T1DM），2219 名患有 2 型糖尿病（T2DM）。平均年龄为 48.4±10.7 岁，其中女性 1128 人，男性 1193 人。79.9%（1853 人）的糖尿病患者甲状腺功能正常；13.8%（321 人）为亚临床甲状腺功能减退症；3.4%（79 人）为临床甲状腺功能减退症，2.9%（68 人）为甲状腺功能亢进症。T2DM 中 14.1%存在亚临床甲状腺功能减退症，而 T1DM 中常见临床甲状腺功能减退症（6.9%）。
应高度怀疑糖尿病患者甲状腺功能障碍，对其进行甲状腺功能筛查，以便早期发现和有效管理两种疾病。
