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2020 年 4 月,也门首都萨那首批卫生工作者中出现高二次感染的 COVID-19 病例:经验教训与未来机遇。

First COVID-19 cases with high secondary infection among health workers, Sana'a capital, April 2020: Lessons learned and future opportunities.

机构信息

Field Epidemiology Training Program, Ministry of Public Health and Papulation, Sana'a, Yemen.

Field Epidemiology Training Program, Ministry of Public Health and Papulation, Sana'a, Yemen.

出版信息

Int J Infect Dis. 2021 Oct;110 Suppl 1:S6-S10. doi: 10.1016/j.ijid.2021.04.022. Epub 2021 Apr 22.

DOI:10.1016/j.ijid.2021.04.022
PMID:33895407
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8061627/
Abstract

OBJECTIVES

Confirm existence of COVID-19 outbreak, conduct contact tracing, and recommend control measures.

METHODS

Two COVID-19 cases in Sana'a Capital met the WHO case definition. Data were collected from cases and contacts who were followed for 14 days. Nasopharyngeal swabs were taken for confirmation by Polymerase Chain Reaction (PCR).

RESULTS

Two confirmed Yemeni male patients aged 20 and 40 years who had no travel history were admitted to hospital on 24 April 2020. Regarding the first patient, symptoms started on April 18th, 2020 then the patient improved and was discharged on May 5th, while the second patient's symptoms started on April 22nd but the patient died on April 29th, 2020. Both patients had 54 contacts, 17 (32%) were health workers (HWs). Four contacts (7%) were confirmed, two of them were HWs that needed hospitalization. The secondary attack rate (sAR) was 12% among HWs compared to 5% among other contacts.

CONCLUSIONS

First COVID-19 outbreak was confirmed among Yemeni citizens with a high sAR among HWs. Strict infection control among HWs should be ensured. Physical distancing and mask-wearing with appropriate disinfecting measures should be promoted especially among contacts. There is a need to strengthen national capacities to assess, detect, and respond to public health emergencies.

摘要

目的

确认新冠疫情的爆发情况,开展接触者追踪,并提出控制措施建议。

方法

两名居住在萨那首都的新冠病例符合世卫组织的病例定义。从对接受为期 14 天追踪的病例和接触者收集数据。采集鼻咽拭子,通过聚合酶链反应(PCR)进行确诊。

结果

2020 年 4 月 24 日,两名分别为 20 岁和 40 岁的也门男性确诊患者住院。第一位患者的症状于 4 月 18 日开始,随后于 5 月 5 日好转出院;第二位患者的症状于 4 月 22 日开始,但于 4 月 29 日死亡。两名患者共有 54 名接触者,其中 17 人(32%)为卫生工作者(HWs)。4 名接触者(7%)检测结果为阳性,其中 2 名 HWs 需要住院治疗。HWs 的二代发病率(sAR)为 12%,而其他接触者的二代发病率为 5%。

结论

也门首例新冠疫情确诊病例为本国公民,HWs 的二代发病率较高。应确保 HWs 严格执行感染控制措施。特别应在接触者中推广保持社交距离和佩戴口罩,并辅以适当的消毒措施。有必要加强国家评估、检测和应对突发公共卫生事件的能力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b9d2/8061627/4be4744b1652/gr1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b9d2/8061627/4be4744b1652/gr1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b9d2/8061627/4be4744b1652/gr1_lrg.jpg

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