Service de Médecine et Santé au Travail, Hôpital de la Timone, APHM, 264, Rue Saint Pierre, 13005, Marseille, France.
Laboratoire de Virologie, IHU Méditerranée Infection, CLIN, CHU Timone, UMR 190-Emergence des Pathologies Virales, Marseille, France.
Int Arch Occup Environ Health. 2022 Mar;95(2):419-424. doi: 10.1007/s00420-021-01789-6. Epub 2021 Oct 15.
SARS-CoV-2, which causes COVID-19, is a virus that has caused a global pandemic. Health workers (HWs) are major players in the fight against this infection and are occupationally exposed to the virus in the course of their work. In this context, this study presents surveillance data on 1714 workers in a hospital center in the south of France for the period from March 17 to April 20, 2020.
Symptomatic HWs, contact cases and those with high anxiety were tested. Diagnosis of COVID-19 was performed by RT-PCR after nasopharyngeal sampling.
During this period, 30.4% of hospital staff received 3028 nasal swabs. Of these, 8.0% were infected with SARS-CoV-2. Among the SARS-CoV-2 positive HWs, 24.3% were asymptomatic. Among COVID unit and non COVID unit, the positive HWs for SARS-CoV-2 were, respectively, 5.8% and 8.2% (p = 0.2). HWs over 50 years of age were less likely to be positive for SARS-CoV-2 (3.8%) than other younger HWs (9.1%) (p < 0.001). No serious cases of COVID-19 were reported in our population during this period.
Our study suggests that HWs who tested positive for COVID-19 are often asymptomatic. Therefore, PPE is pivotal to prevent HWs to patients and HWs to HWs transmission during workshifts. Contact tracing and screening is essential to limit the spread of the virus within the hospital. On the other hand, HWs working in COVID-19 units are not more often infected probably because they have a higher risk awareness than other HWs.
导致 COVID-19 的 SARS-CoV-2 是一种在全球范围内引发大流行的病毒。医护人员（HWs）是抗击这种感染的主要力量，在工作过程中会接触到这种病毒。在这种情况下，本研究报告了 2020 年 3 月 17 日至 4 月 20 日期间法国南部一家医院中心的 1714 名工作人员的监测数据。
对出现症状的 HWs、接触病例和焦虑程度高的 HWs 进行检测。COVID-19 的诊断通过鼻咽取样后进行 RT-PCR 进行。
在此期间，30.4%的医院工作人员接受了 3028 次鼻拭子检测。其中，8.0%的人感染了 SARS-CoV-2。在 SARS-CoV-2 阳性的 HWs 中，24.3%无症状。在 COVID 病房和非 COVID 病房中，HWs 的 SARS-CoV-2 阳性率分别为 5.8%和 8.2%（p=0.2）。年龄超过 50 岁的 HWs 感染 SARS-CoV-2 的可能性（3.8%）低于其他年轻 HWs（9.1%）（p<0.001）。在此期间，我们的人群中没有报告严重的 COVID-19 病例。
我们的研究表明，COVID-19 检测呈阳性的 HWs 通常无症状。因此，PPE 对于防止 HWs 在轮班期间将病毒传播给患者和 HWs 至关重要。接触者追踪和筛查对于限制病毒在医院内的传播至关重要。另一方面，HWs 在 COVID-19 病房工作时感染的可能性并不高，这可能是因为他们比其他 HWs 具有更高的风险意识。
