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沙特内分泌学会(SSEM)发布的 2 型糖尿病药物治疗共识声明

Pharmacological treatment of type 2 diabetes in Saudi Arabia: A consensus statement from the Saudi Society of Endocrinology and Metabolism (SSEM).

机构信息

Division of Endocrinology, Department of Internal Medicine, College of Medicine, King Saud University, Riyadh, Saudi Arabia; Division of Endocrinology, Diabetes & Metabolism, the Johns Hopkins University, Baltimore, MD, USA; Strategic Center for Diabetes Research, College of Medicine, King Saud University, Riyadh, Saudi Arabia.

Department of Family and Community Medicine, College of Medicine, King Saud University, Riyadh, Saudi Arabia.

出版信息

Diabetes Metab Syndr. 2021 May-Jun;15(3):891-899. doi: 10.1016/j.dsx.2021.04.003. Epub 2021 Apr 20.

Abstract

BACKGROUND AND AIMS

The list of available treatment options for managing blood glucose in patients with type 2 diabetes (T2D) has grown over recent years making the task of choosing between traditional and newer glucose-lowering agents a difficult one for healthcare providers.

METHODS

We summarize treatment algorithms developed by popular professional societies and propose a patient-centered and culture-driven recommendations for selecting diabetes medications for people with T2D in Saudi Arabia.

RESULTS

Though most professional societies recognize patient's adherence to medications as an important factor in achieving glycemic targets, published algorithms schemes do not formally enlist adherence to medication as a deciding factor in the choice of glucose-lowering agents. Medication appeal to patients, an important determinant of medication adherence, is influenced by several factors including lifestyle, common beliefs, customs and traditions, health literacy, perception of health and disease, socioeconomic and cultural backgrounds, and religious commitments and obligations. In Saudi Arabia, poor adherence to therapy is a major obstacle to effective management of local people with T2D.

CONCLUSIONS

The Saudi population has a unique socioeconomic and cultural background that widely respect adherence to religion and culture; and the applicability of international guidelines for the management of T2D to the Saudi population has been called into question. In this consensus statement, we propose patient-centered and culture-driven recommendations that integrate medication-adherence and medication-cost into overall selection of diabetes medications for people with T2D in Saudi Arabia.

摘要

背景和目的

近年来,可供 2 型糖尿病(T2D)患者管理血糖的治疗选择方案有所增加,这使得医疗保健提供者在选择传统和新型降糖药物方面面临困难。

方法

我们总结了一些受欢迎的专业协会制定的治疗方案,并针对沙特阿拉伯 T2D 患者提出了一种以患者为中心且受文化驱动的选择糖尿病药物的建议。

结果

虽然大多数专业协会都认识到患者对药物的依从性是实现血糖目标的重要因素,但已发表的方案并未将药物依从性正式列为选择降糖药物的决定因素。药物对患者的吸引力是药物依从性的重要决定因素,它受到多种因素的影响,包括生活方式、常见信念、习俗和传统、健康素养、对健康和疾病的认知、社会经济和文化背景以及宗教承诺和义务。在沙特阿拉伯,治疗依从性差是有效管理当地 T2D 患者的主要障碍。

结论

沙特人口具有独特的社会经济和文化背景,他们普遍尊重对宗教和文化的遵守;国际 T2D 管理指南在沙特人口中的适用性也受到质疑。在本共识声明中,我们提出了以患者为中心且受文化驱动的建议,将药物依从性和药物费用纳入沙特阿拉伯 T2D 患者选择糖尿病药物的整体考虑中。

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