Asher E F, Oliver B G, Fry D E
Department of Surgery, University of Louisville School of Medicine, Kentucky 40292.
Am Surg. 1988 Jul;54(7):466-9.
Urinary tract infection (UTI) continues to be a common nosocomial infection. From a 2-year city-county hospital experience, 212 nosocomial UTI were identified in 153 patients from 3747 admissions. Mean age was 54 years; 102 were men. Foley catheterization was an associated factor in 129 patients (84%). UTI was caused by 40 different species of bacteria. In 28 infections (13%), the UTI was polymicrobial. Only nine patients had bacteremia. The bacteriology of the UTI depended on whether the patient had received systemic antibiotics previously during the hospitalization. Prior antibiotic administration increased the probability of Pseudomonas and Serratia as pathogens. Thus, patients that have had antibiotic therapy demonstrate a distribution of pathogens that are different from patients not receiving antibiotics, and a distribution different from the community-acquired UTI. Continued emphasis on the shorter duration and more judicious use of systemic antibiotics for both prophylaxis and therapy is warranted.
尿路感染(UTI)仍然是一种常见的医院感染。根据一家市县医院两年的经验,在3747例住院患者中,153例患者发生了212例医院获得性UTI。平均年龄为54岁;男性102例。129例患者(84%)的相关因素为留置导尿管。UTI由40种不同的细菌引起。在28例感染(13%)中,UTI为多种微生物感染。只有9例患者发生菌血症。UTI的细菌学取决于患者在住院期间之前是否接受过全身抗生素治疗。先前使用抗生素增加了铜绿假单胞菌和沙雷氏菌作为病原体的可能性。因此,接受过抗生素治疗的患者表现出与未接受抗生素治疗的患者不同的病原体分布,且与社区获得性UTI的分布也不同。有必要继续强调缩短全身抗生素预防和治疗的持续时间并更明智地使用。