Shimpi Rajendra K, Patel Darshan N, Raval Krutik, Shah Priyank, Shah Bonny
Department of Urology, Ruby Hall Clinic, Pune, Maharshtra, India.
Urol Ann. 2021 Jan-Mar;13(1):19-23. doi: 10.4103/UA.UA_119_19. Epub 2021 Jan 19.
Orthotopic neobladder is a well-established technique for continent urinary diversion after radical cystectomy. In this study, we evaluated a new Frog ileal neobladder technique. Since the reconstructed neobladder appears like a frog, the name Frog Neobladder was given to it. We have used two isoperistaltic ileal segments and implanted ureters in the nondetubularized proximal end of the ileal segment.
This was a prospective, single-center (tertiary care hospital) study conducted from February 2008 to January 2018. Study patients were aged 39-94 years with biopsy-proven muscle-invasive localized bladder carcinoma. One hundred and twenty patients were included in the study, who had undergone Radical Cystectomy and were offered "FROG BLADDER"- a type of neobladder. Evaluation of complications, renal function, urodynamic parameters, post-void residual urine (PVR), continence, and need for clean intermittent catheterization was done in all patients with neobladder.
A total of 120 patients were included in the study, the average age of the patients was 62 years. The operative mean time was 280 ± 29.8 min. There was no perioperative death, and perioperative or early and late complication rates were 31.2% and 18.7%, respectively. Six patients had uretero-enteric anastomosis stricture, of which two were managed by retrograde ureteroscopic dilatation, another three strictures were treated with antegrade approach, and one patient underwent open surgery. All patients were able to void urine, except for three patients who required self-catheterization. The mean capacity was increased to average of 398 ± 220 ml at 12 months in all patients. The mean PVR at 1 year was 46 ± 54.4 ml.
The Frog neobladder has similar outcome similar to other neobladder technique, with added advantage of ability to accommodate shorter ureteric length and the ease of accessing ureter by retrograde approach for intervention.
原位新膀胱是根治性膀胱切除术后成熟的可控性尿流改道术。在本研究中,我们评估了一种新的青蛙回肠新膀胱技术。由于重建的新膀胱形似青蛙,故将其命名为青蛙新膀胱。我们使用了两段等蠕动的回肠段,并将输尿管植入回肠段未去管化的近端。
这是一项于2008年2月至2018年1月进行的前瞻性单中心(三级护理医院)研究。研究患者年龄在39 - 94岁之间,经活检证实为肌层浸润性局限性膀胱癌。120例患者纳入研究,他们均接受了根治性膀胱切除术,并接受了“青蛙膀胱”——一种新膀胱。对所有新膀胱患者进行了并发症、肾功能、尿动力学参数、排尿后残余尿量(PVR)、控尿能力以及清洁间歇性导尿需求的评估。
共有120例患者纳入研究,患者平均年龄为62岁。手术平均时间为280 ± 29.8分钟。无围手术期死亡,围手术期及早期和晚期并发症发生率分别为31.2%和18.7%。6例患者发生输尿管肠吻合口狭窄,其中2例通过逆行输尿管镜扩张处理,另外3例狭窄采用顺行方法治疗,1例患者接受了开放手术。除3例需要自我导尿的患者外,所有患者均能自行排尿。所有患者在12个月时平均容量增加至平均398 ± 220毫升。1年时平均PVR为46 ± 54.4毫升。
青蛙新膀胱的结果与其他新膀胱技术相似,其额外优势在于能够适应较短的输尿管长度,且通过逆行途径易于进入输尿管进行干预。