Sharma Neha, Ostas Daniel, Rotar Horatiu, Brantner Philipp, Thieringer Florian Markus
Clinic of Oral and Cranio-Maxillofacial Surgery, University Hospital Basel, Basel, Switzerland.
Department of Biomedical Engineering, Medical Additive Manufacturing Research Group (SwissMAM), University of Basel, Allschwil, Switzerland.
Front Physiol. 2021 Apr 9;12:647923. doi: 10.3389/fphys.2021.647923. eCollection 2021.
Reconstruction of cranial defects is an arduous task for craniomaxillofacial surgeons. Additive manufacturing (AM) or three-dimensional (3D) printing of titanium patient-specific implants (PSIs) made its way into cranioplasty, improving the clinical outcomes in complex surgical procedures. There has been a significant interest within the medical community in redesigning implants based on natural analogies. This paper proposes a workflow to create a biomimetic patient-specific cranial prosthesis with an interconnected strut macrostructure mimicking bone trabeculae. The method implements an interactive generative design approach based on the Voronoi diagram or tessellations. Furthermore, the quasi-self-supporting fabrication feasibility of the biomimetic, lightweight titanium cranial prosthesis design is assessed using Selective Laser Melting (SLM) technology.
颅骨缺损修复对于颅颌面外科医生来说是一项艰巨的任务。钛定制植入物（PSI）的增材制造（AM）或三维（3D）打印已应用于颅骨成形术，改善了复杂外科手术的临床效果。医学界对基于自然类比重新设计植入物有着浓厚兴趣。本文提出了一种工作流程，以创建具有模仿骨小梁的相互连接支柱宏观结构的仿生定制颅骨假体。该方法基于Voronoi图或镶嵌实现交互式生成设计方法。此外，使用选择性激光熔化（SLM）技术评估了仿生轻质钛颅骨假体设计的准自支撑制造可行性。
