Jones H R, Ho D D, Forgacs P, Adelman L S, Silverman M L, Baker R A, Locuratolo P
Department of Neurology, Lahey Clinic Medical Center, Burlington, MA 01805.
Ann Neurol. 1988 May;23(5):519-22. doi: 10.1002/ana.410230515.
A case of acute human immunodeficiency virus (HIV) infection manifested by a rapidly fulminating, necrotizing, demyelinating encephalopathy that led to brain death in 5 days is reported. Autopsy demonstrated predominant white matter lesions, acute neuronal damage, and scanty cellular response. Cultures of cerebrospinal fluid were positive for HIV, suggesting an acute infection.
报告了一例急性人类免疫缺陷病毒（HIV）感染病例，其表现为迅速爆发的坏死性脱髓鞘性脑病，5天内导致脑死亡。尸检显示主要为白质病变、急性神经元损伤和轻微的细胞反应。脑脊液培养HIV呈阳性，提示急性感染。
