Saris S C, Iacono R P, Nashold B S
Surgical Neurology Branch, National Institute of Neurological and Communicative Disorders and Stroke, Bethesda, Md.
Appl Neurophysiol. 1988;51(2-5):188-97. doi: 10.1159/000099962.
We studied 22 patients with amputation due to trauma, gangrene, or cancer. All developed postamputation pain, underwent a dorsal root entry zone (DREZ) procedure, and were followed from 6 months to 4 years after surgery. Overall, only 8 (36%) of these 22 patients had pain relief. However, good results were obtained in 6 (67%) of 9 patients with phantom pain alone, and in 5 (83%) of 6 patients with traumatic amputations associated with root avulsion. Poor results were obtained in patients with both phantom and stump pain, or stump pain alone. The DREZ procedure has a well-defined, but limited role in the treatment of postamputation pain.
我们研究了22例因创伤、坏疽或癌症而截肢的患者。所有患者均出现了截肢后疼痛，接受了背根入髓区（DREZ）手术，并在术后6个月至4年进行随访。总体而言，这22例患者中只有8例（36%）疼痛得到缓解。然而，仅患有幻肢痛的9例患者中有6例（67%）取得了良好效果，与神经根撕脱相关的创伤性截肢的6例患者中有5例（83%）取得了良好效果。同时患有幻肢痛和残端痛或仅患有残端痛的患者效果较差。DREZ手术在截肢后疼痛的治疗中具有明确但有限的作用。
