Tourian A, Iacono R, Nashold B, Urban B, Sanders D
Department of Medicine (Neurology), Duke University Medical Center, Durham, N.C.
Appl Neurophysiol. 1988;51(2-5):212-7. doi: 10.1159/000099965.
A patient developed continuous patterned involuntary movements of abduction-adduction, flexion-extension of his right lower extremity following surgical placement of spinal dorsal root entry zone lesions for the treatment of phantom limb pain. The stereotype movements were monitored by video and electromyographic recording of quadriceps femoris and hamstring muscles. Administration of para-chlorophenylbutyric acid (baclofen) dramatically stopped the involuntary movements and electromyographic silence ensued. Voluntary muscle movements were preserved. The theoretical implications of this unique movement disorder and central patterning of motor activity within the spinal cord are discussed.
一名患者在接受脊髓背根进入区损伤手术以治疗幻肢痛后，出现了右下肢持续的、有规律的外展-内收、屈伸的不自主运动。通过视频以及股四头肌和腘绳肌的肌电图记录对刻板运动进行了监测。给予对氯苯丁酸（巴氯芬）后，不自主运动显著停止，随后肌电图显示静息。自主肌肉运动得以保留。讨论了这种独特运动障碍以及脊髓内运动活动的中枢模式化的理论意义。
