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在一家儿科急诊科就诊的有症状患者中，SARS-CoV-2感染率较低。

Low Rate of SARS-CoV-2 Infections in Symptomatic Patients Attending a Pediatric Emergency Department.

作者信息

Zurl Christoph, Eber Ernst, Siegl Anna, Loeffler Sabine, Stelzl Evelyn, Kessler Harald H, Egger Markus, Schweintzger Nina A, Zenz Werner, Strenger Volker

机构信息

Division of General Pediatrics, Department of Pediatrics and Adolescent Medicine, Medical University Graz, Graz, Austria.

Section of Infectious Diseases and Tropical Medicine, Department of Internal Medicine, Medical University Graz, Graz, Austria.

出版信息

Front Pediatr. 2021 Apr 9;9:637167. doi: 10.3389/fped.2021.637167. eCollection 2021.

DOI:10.3389/fped.2021.637167
PMID:33898359
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8064389/
Abstract

Children and adolescents seem to be at lower risk of developing clinical symptoms of COVID-19. We analyzed the rate of SARS-CoV-2 infections among 3,605 symptomatic children and adolescents at 4,402 outpatient visits presenting to a pediatric emergency department. In a total of 1,105 (32.6%) episodes, the patients fulfilled clinical case definitions for SARS-CoV-2 infection and were tested by nucleic acid testing. A SARS-CoV-2 infection was diagnosed in 10/1,100 episodes (0.3% of analyzed episodes, 0.91% of validly tested patients). Symptoms at presentation did not differ between patients with and without SARS-CoV-2 infection, apart from the frequency of measured temperature ≥37.5°C at presentation. Three percent of analyzed children reported disturbances of olfactory or gustatory senses, but none of them was infected with SARS-CoV-2. The rate of SARS-CoV-2 infections among symptomatic children and adolescents was low and SARS-CoV-2 infections could not reliably be differentiated from other infections without nucleic acid testing.

摘要

儿童和青少年出现新冠病毒病临床症状的风险似乎较低。我们分析了在一家儿科急诊科就诊的4402人次门诊中，3605名有症状儿童和青少年的新冠病毒感染率。在总共1105例（32.6%）病例中，患者符合新冠病毒感染的临床病例定义并接受了核酸检测。在1100例病例中有10例被诊断为新冠病毒感染（占分析病例的0.3%，有效检测患者的0.91%）。除了就诊时测量体温≥37.5°C的频率外，有和没有新冠病毒感染的患者就诊时的症状没有差异。3%的分析儿童报告有嗅觉或味觉障碍，但他们中没有人感染新冠病毒。有症状儿童和青少年中的新冠病毒感染率较低，在没有核酸检测的情况下，无法可靠地将新冠病毒感染与其他感染区分开来。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3b7b/8064389/1ccc83d5abd5/fped-09-637167-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3b7b/8064389/1ccc83d5abd5/fped-09-637167-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3b7b/8064389/1ccc83d5abd5/fped-09-637167-g0001.jpg

相似文献

[1]
Low Rate of SARS-CoV-2 Infections in Symptomatic Patients Attending a Pediatric Emergency Department.

Front Pediatr. 2021-4-9

[2]
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[3]
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引用本文的文献

[1]
COVID-19 Screening in the Pediatric Emergency Department.

Cureus. 2023-3-3

[2]
Signs and symptoms to determine if a patient presenting in primary care or hospital outpatient settings has COVID-19.

Cochrane Database Syst Rev. 2022-5-20

[3]
Management of patients with SARS-CoV-2 infections with focus on patients with chronic lung diseases (as of 10 January 2022) : Updated statement of the Austrian Society of Pneumology (ASP).

Wien Klin Wochenschr. 2022-5

[4]
Covid-19 Incidence and Mortality by Age Strata and Comorbidities in Mexico City: A Focus in the Pediatric Population.

Front Public Health. 2021

本文引用的文献

[1]
Coronavirus Disease 2019 Pandemic: Impact Caused by School Closure and National Lockdown on Pediatric Visits and Admissions for Viral and Nonviral Infections-a Time Series Analysis.

Clin Infect Dis. 2021-1-27

[2]
Characterisation of 22445 patients attending UK emergency departments with suspected COVID-19 infection: Observational cohort study.

PLoS One. 2020-11-25

[3]
Assessment of 135 794 Pediatric Patients Tested for Severe Acute Respiratory Syndrome Coronavirus 2 Across the United States.

JAMA Pediatr. 2021-2-1

[4]
Paediatric patients seen in 18 emergency departments during the COVID-19 pandemic.

Emerg Med J. 2020-10-29

[5]
Susceptibility to SARS-CoV-2 Infection Among Children and Adolescents Compared With Adults: A Systematic Review and Meta-analysis.

JAMA Pediatr. 2021-2-1

[6]
Austrian study shows that delays in accessing acute paediatric health care outweighed the risks of COVID-19.

Acta Paediatr. 2020-11

[7]
European and United Kingdom COVID-19 pandemic experience: The same but different.

Paediatr Respir Rev. 2020-7-4

[8]
COVID-19 in children and adolescents in Europe: a multinational, multicentre cohort study.

Lancet Child Adolesc Health. 2020-6-25

[9]
Management of patients with SARS-CoV-2 infections and of patients with chronic lung diseases during the COVID-19 pandemic (as of 9 May 2020) : Statement of the Austrian Society of Pneumology (ASP).

Wien Klin Wochenschr. 2020-7

[10]
Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in China: Summary of a Report of 72 314 Cases From the Chinese Center for Disease Control and Prevention.

JAMA. 2020-4-7

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