Branderhorst Woutjan, Steensma Bart R, Beijst Casper, Huijing Erik R, Alborahal Cezar, Versteeg Edwin, Weissler Bjoern, Schug David, Gebhardt Pierre, Gross-Weege Nicolas, Mueller Florian, Krueger Karl, Dey Thomas, Radermacher Harald, Lips Oliver, Lagendijk Jan, Schulz Volkmar, de Jong Hugo W A M, Klomp Dennis W J
Department of Radiology and Nuclear Medicine, University Medical Center Utrecht, Utrecht, The Netherlands.
Department of Physics of Molecular Imaging Systems, RWTH Aachen University, Aachen, Germany.
Phys Imaging Radiat Oncol. 2020 Dec 23;17:13-19. doi: 10.1016/j.phro.2020.12.002. eCollection 2021 Jan.
The restricted bore diameter of current simultaneous positron emission tomography/magnetic resonance imaging (PET/MRI) systems can be an impediment to achieving similar patient positioning during PET/MRI planning and radiotherapy. Our goal was to evaluate the B transmit (B ) uniformity, B efficiency, and specific absorption rate (SAR) of a novel radiofrequency (RF) body coil design, in which RF shielded PET detectors were integrated with the specific aim of enabling a wide-bore PET/MRI system.
We designed and constructed a wide-bore PET/MRI RF body coil to be integrated with a clinical MRI system. To increase its inner bore diameter, the PET detectors were positioned between the conductors and the RF shield of the RF body coil. Simulations and experiments with phantoms and human volunteers were performed to compare the B uniformity, B efficiency, and SAR between our design and the clinical body coil.
In the simulations, our design achieved nearly the same B field uniformity as the clinical body coil and an almost identical SAR distribution. The uniformity findings were confirmed by the physical experiments. The B efficiency was 38% lower compared to the clinical body coil.
To achieve wide-bore PET/MRI, it is possible to integrate shielding for PET detectors between the body coil conductors and the RF shield without compromising MRI performance. Reduced B efficiency may be compensated by adding a second RF amplifier. This finding may facilitate the application of simultaneous whole-body PET/MRI in radiotherapy planning.
当前同时正电子发射断层扫描/磁共振成像(PET/MRI)系统受限的孔径可能会妨碍在PET/MRI规划和放射治疗期间实现相似的患者定位。我们的目标是评估一种新型射频(RF)体线圈设计的B传输(B)均匀性、B效率和比吸收率(SAR),该设计将RF屏蔽的PET探测器集成在一起,旨在实现大孔径PET/MRI系统。
我们设计并构建了一个与临床MRI系统集成的大孔径PET/MRI RF体线圈。为了增加其内径,将PET探测器放置在RF体线圈的导体和RF屏蔽之间。使用体模和人类志愿者进行了模拟和实验,以比较我们的设计与临床体线圈之间的B均匀性、B效率和SAR。
在模拟中,我们的设计实现了与临床体线圈几乎相同的B场均匀性和几乎相同的SAR分布。物理实验证实了均匀性结果。与临床体线圈相比,B效率低38%。
为了实现大孔径PET/MRI,可以在体线圈导体和RF屏蔽之间集成PET探测器的屏蔽,而不会影响MRI性能。降低的B效率可以通过添加第二个RF放大器来补偿。这一发现可能有助于在放射治疗规划中应用同时全身PET/MRI。