Chen Xiaofang, Liu Jianzhong, Yao Qianyu, Chen Xianyi
Suzhou Industrial Park Centers for Disease Control and Prevention, Suzhou, Jiangsu 215021, P.R.China.
Beijing Zhongyi Health Research Institute, Beijing 100089, P.R.China.
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2021 Feb 25;38(1):154-160. doi: 10.7507/1001-5515.202011038.
The cold chain safety of vaccines is a global issue. The electronic vaccine vial monitor (eVVM) label can monitor the temperature of vaccines in real time and provide "early warning" prompts. In order to comprehensively evaluate the monitoring efficiency of eVVM, this study selected 75 eVVM labels and distributed them with a total of 600 vaccine vial monitor (VVM) labels of four different types in different experimental environment (2-8℃, -20℃ and 40℃), and used a temperature recorder as "gold standard". The results showed that the accuracy of the eVVM labels and VVM labels in high temperature environment was as same as that of the temperature recorder ( = 0.195). The accuracy of low temperature anomalies report and high temperature anomalies report of eVVM labels was 100%, which was better than those reported by VVM labels. Therefore, eVVM labels have high monitoring accuracy, which is suitable not only for ordinary environments, but also for severe temperature environments. It should be helpful for the improvement of the efficiency and accuracy of cold chain monitoring.
疫苗冷链安全是一个全球性问题。电子疫苗瓶监测器（eVVM）标签能够实时监测疫苗温度并提供“预警”提示。为全面评估eVVM的监测效率，本研究选取了75个eVVM标签，并在不同实验环境（2-8℃、-20℃和40℃）中与总共600个四种不同类型的疫苗瓶监测器（VVM）标签一起分发，同时使用温度记录仪作为“金标准”。结果显示，eVVM标签和VVM标签在高温环境下的准确性与温度记录仪相同（ = 0.195）。eVVM标签的低温异常报告和高温异常报告的准确率均为100%，优于VVM标签报告的结果。因此，eVVM标签具有较高的监测准确性，不仅适用于普通环境，也适用于极端温度环境。这应该有助于提高冷链监测的效率和准确性。
