Lescoat D, Colleu D, Boujard D, Le Lannou D
Unité de Biologie de la Reproduction, Laboratoire d'Histologie et d'Embryologie, Rennes, France.
Arch Androl. 1988;20(1):35-40. doi: 10.3109/01485018808987050.
A comparative electrophoretic analysis of nuclear proteins was investigated in ejaculated human semen. The results confirm the biochemical heterogeneity of nucleoproteins in sperm with normal routine parameters and demonstrate the same heterogeneity in semen with defective routine parameters: nucleoproteins comprise histones, intermediate proteins, and protamines in the two groups. Individual qualitative and quantitative differences are observed within and between the two groups. The results allow a better knowledge of nuclear characteristics of ejaculated human spermatozoa but it does not permit the establishment of a relationship between biochemical heterogeneity of sperm nucleus and decreased fertility.
对射出的人类精液中的核蛋白进行了比较电泳分析。结果证实了常规参数正常的精子中核蛋白的生化异质性,并表明常规参数有缺陷的精液中也存在同样的异质性:两组中的核蛋白均包括组蛋白、中间蛋白和鱼精蛋白。在两组内部和两组之间均观察到了个体的定性和定量差异。这些结果有助于更好地了解射出的人类精子的核特征,但无法确定精子细胞核的生化异质性与生育力下降之间的关系。