Medical School, Xi'an Peihua University, Xi'an 710125, Shaanxi, China.
School of Chemical Engineering and Technology, Xi'an Jiaotong University, Xi'an, Shaanxi 710049, China.
Org Biomol Chem. 2021 Apr 26;19(15):3287-3302. doi: 10.1039/d1ob00222h.
A combination of Nobel macrocycle-crown ether and star macrocycle-pillararenes together in organic synthesis and material science is significant in obtaining hybrid systems, with rigid/flexible structural architecture, induced planar chirality, a negative cooperative effect and multiple fused cyclic hosts. In this review, we will discuss the synthesis/preparation of crown ether-pillararene hybrid macrocyclic systems by covalent bonds, supramolecular interactions and mechanical bonds, leading to hybrid compounds, supramolecular assemblies and mechanically interlocked molecules. The practical applications of crown ether-containing pillararenes will also be discussed in diverse areas, such as molecular recognition via fused multiple macrocycles and ion channels as well as external stimuli-responsive smart materials. We also call the attention of related researchers towards academic and technical issues about topological structures and applied functions in this fresh new fused macrocyclic field.
冠醚-杯芳烃杂化大环体系的构筑及应用研究进展
冠醚-杯芳烃杂化大环体系的构筑及应用研究进展。本文综述了通过共价键、超分子相互作用和机械键将冠醚-杯芳烃杂化大环体系的合成/制备，得到杂化化合物、超分子组装体和机械互锁分子。还讨论了含冠醚的杯芳烃在分子识别（通过多个大环的融合）、离子通道以及对外界刺激响应的智能材料等多个领域的实际应用。我们还呼吁相关研究人员关注这一新兴的融合大环领域在拓扑结构和应用功能方面的相关学术和技术问题。
