Abdin Alaa Din, Suffo Shady, Fries Fabian N, Kaymak Hakan, Seitz Berthold
Klinik für Augenheilkunde, Universitätsklinikum des Saarlandes UKS, Kirrberger Str. 100, Gebäude 22, 66421, Homburg/Saar, Deutschland.
Internationale Innovative Ophthalmochirurgie (I. I. O.), 40549, Düsseldorf, Deutschland.
Ophthalmologe. 2021 Aug;118(8):865-878. doi: 10.1007/s00347-021-01379-4. Epub 2021 Apr 26.
Pachychoroid spectrum disorders are characterized by a thickening of the choroid. The spectrum includes pachychoroid pigment epitheliopathy (PPE), central serous chorioretinopathy (CCS), pachychoroid neovasculopathy (PNV), polypoidal choroidal vasculopathy (PCV)/aneurysmal type 1 choroidal neovascularization (ACNV-1), focal choroidal excavation (FCE) and peripapillary pachychoroid syndrome (PPS). If the choroid is thickened and there is a pathological alteration in the retinal pigment epithelium, the diagnosis is PPE; if the thickened choroid is accompanied by subretinal fluid, the diagnosis is CCS; if choroidal neovascularization is present, the diagnosis is PNV; if accompanied by aneurysms, the diagnosis is ACNV‑1. The PPE, CCS, PNV and ACNV‑1 were formerly regarded as independent disease entities but can be classified into four forms of a single disease family, pachychoroid macular disease.
厚脉络膜谱系疾病的特征是脉络膜增厚。该谱系包括厚脉络膜色素上皮病变（PPE）、中心性浆液性脉络膜视网膜病变（CCS）、厚脉络膜新生血管病变（PNV）、息肉样脉络膜血管病变（PCV）/1型动脉瘤样脉络膜新生血管（ACNV-1）、局限性脉络膜凹陷（FCE）和视盘周围厚脉络膜综合征（PPS）。如果脉络膜增厚且视网膜色素上皮存在病理改变，则诊断为PPE；如果增厚的脉络膜伴有视网膜下液，则诊断为CCS；如果存在脉络膜新生血管，则诊断为PNV；如果伴有动脉瘤，则诊断为ACNV-1。PPE、CCS、PNV和ACNV-1以前被视为独立的疾病实体，但可归类为单一疾病家族的四种形式，即厚脉络膜黄斑疾病。
