Angeles Pedregal Hospital, Assisted Reproduction Unit, Mexico City, Mexico.
JBRA Assist Reprod. 2021 Jul 21;25(3):447-452. doi: 10.5935/1518-0557.20210007.
This study aimed to examine the association between serum estradiol levels and number of metaphase II oocytes harvested after in vitro fertilization cycles used in embryo transfers and the subsequent impact on pregnancy rates.
This observational analytical retrospective study was carried out in 2010-2018 at the Angeles del Pedregal Hospital. It included 181 cases and looked into the number of metaphase II oocytes to predict pregnancy rates. Statistical analysis was based on the calculation of correlations between variables and logistic regressions.
Estradiol levels increased with the number of oocytes by a median correlation (r=0.482, p=0.000). On the day of trigger, estradiol levels predicted the number of retrieved oocytes with 23% reliability (R2=0.232, p=0.000); a linear trend correlation of r=0.489, p=0.000 was found between estradiol levels on the day of trigger and number of metaphase II oocytes.
Serum estradiol on the day of trigger as a predictor of metaphase II oocytes in antagonist cycles encourages greater oocyte maturity and fertilization, whereas, in isolation, it does not determine the pregnancy achievement.
本研究旨在探讨体外受精周期中血清雌二醇水平与收获的中期 II 卵母细胞数量与胚胎移植后妊娠率之间的关系及其后续影响。
本观察性分析回顾性研究于 2010 年至 2018 年在安赫莱斯德尔佩德雷加尔医院进行。共纳入 181 例病例，研究了中期 II 卵母细胞的数量以预测妊娠率。统计分析基于变量之间相关性的计算和逻辑回归。
雌二醇水平随卵母细胞数量中位数相关（r=0.482，p=0.000）增加。在触发日，雌二醇水平预测取卵数量的可靠性为 23%（R2=0.232，p=0.000）；在触发日雌二醇水平与中期 II 卵母细胞数量之间发现线性趋势相关性 r=0.489，p=0.000。
作为拮抗剂周期中中期 II 卵母细胞预测因子的触发日血清雌二醇可促进卵母细胞成熟和受精，但单独使用并不能决定妊娠的实现。
