Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Dipartimento di Scienze Cliniche e di Comunità, Università degli Studi di Milano, Milan, Italy.
PLoS One. 2021 Apr 26;16(4):e0250730. doi: 10.1371/journal.pone.0250730. eCollection 2021.
During the COVID-19 pandemic, the number of individuals needing hospital admission has sometimes exceeded the availability of hospital beds. Since hospitalization can have detrimental effects on older individuals, preference has been given to younger patients. The aim of this study was to assess the utility of hospitalization for elderly affected by COVID-19. We hypothesized that their mortality decreases when there is greater access to hospitals.
This study examined 1902 COVID-19 patients consecutively admitted to three large hospitals in Milan, Italy. Overall mortality data for Milan from the same period was retrieved. Based on emergency department (ED) data, both peak and off-peak phases were identified. The percentage of elderly patients admitted to EDs during these two phases were compared by calculating the standardized mortality ratio (SMR) of the individuals younger than, versus older than, 80 years.
The median age of the patients hospitalized during the peak phase was lower than the median age during the off-peak phase (64 vs. 75 years, respectively; p <0.001). However, while the SMR for the younger patients was lower during the off-peak phase (1.98, 95% CI: 1.72-2.29 versus 1.40, 95% CI: 1.25-1.58, respectively), the SMR was similar between both phases for the elderly patients (2.28, 95% CI: 2.07-2.52 versus 2.48, 95% CI: 2.32-2.65, respectively).
Greater access to hospitals during an off-peak phase did not affect the mortality rate of COVID-19-positive elderly patients in Milan. This finding, if confirmed in other settings, should influence future decisions regarding resource management of health care organizations.
在 COVID-19 大流行期间,需要住院的人数有时超过了医院床位的可用性。由于住院对老年人可能产生不利影响,因此更倾向于优先考虑年轻患者。本研究旨在评估 COVID-19 老年患者住院的效果。我们假设,当老年人更容易获得住院治疗时,其死亡率会降低。
本研究纳入了连续入住意大利米兰三家大型医院的 1902 例 COVID-19 患者。同时检索了同期米兰的总体死亡率数据。根据急诊科(ED)数据,确定了高峰期和非高峰期。通过计算年龄小于 80 岁和大于 80 岁患者的标准化死亡率比(SMR),比较了这两个阶段急诊科收治的老年患者比例。
高峰期住院患者的中位年龄低于非高峰期(分别为 64 岁和 75 岁,p<0.001)。然而,虽然非高峰期年龄较小患者的 SMR 较低(1.98,95%CI:1.72-2.29 与 1.40,95%CI:1.25-1.58 相比),但高峰期和非高峰期老年患者的 SMR 相似(2.28,95%CI:2.07-2.52 与 2.48,95%CI:2.32-2.65 相比)。
在非高峰期增加医院床位的可及性并未影响米兰 COVID-19 阳性老年患者的死亡率。如果这一发现得到其他环境的证实,应影响未来医疗保健组织资源管理的决策。