Division of Geriatrics and Palliative Medicine, New York-Presbyterian Weill Cornell Medical Center, New York, NY, USA.
Department of Medicine, New York-Presbyterian Weill Cornell Medical Center, New York, NY, USA.
J Palliat Care. 2022 Jul;37(3):298-309. doi: 10.1177/08258597221098130. Epub 2022 May 3.
Morbidity and mortality are higher in older adults with COVID-19, but their decisions about aggressive care, severity of disease, and outcomes during the first surge in New York City are not well characterized. We sought to determine if the oldest patients chose intubation and comfort care at different rates compared to younger geriatric patients. We also studied outcomes among patients admitted with severe disease and those who chose aggressive versus comfort care. This retrospective analysis used electronic health record data from patients 65 years and older at two medical centers in New York City admitted between 3/5/2020 and 5/15/2020. The primary outcome was comfort care orders, and secondary outcomes included death, palliative care consultation, goals of care discussion, code status, and ventilator weaning. Of the 854 patients, 214 were in the oldest old (OO, age > = 85) group, 269 middle old (MO, age 75-84), and 371 young old (YO, age 65-74). Among those with serious disease, the OO were more likely to choose comfort care (45% vs. 21% MO and 6.8% YO), less likely to be intubated (17% vs. 37% MO and 44% YO), more likely to have a palliative care consult, more likely to be DNR/DNI on admission (60% vs. 17% MO and 9.3%% YO), and more likely to die during admission (65% vs. 42% MO and 21% YO) (all p-values < 0.001). Of all 216 intubated patients, 78% of the OO died, versus 66% of the MO and 36% of the YO (p = <0.001). Adults 85 and above admitted with COVID-19 were more likely to forego intubation and die with comfort-based care. Irrespective of intubation choice, patients 85 and older had a markedly poorer prognosis than other cohorts over 65.
发病率和死亡率在患有 COVID-19 的老年人中更高,但他们在纽约市第一波疫情期间关于积极治疗、疾病严重程度和结局的决策尚未得到很好的描述。我们试图确定最年长的患者与年轻的老年患者相比,是否以不同的比率选择插管和舒适护理。我们还研究了患有严重疾病的患者和选择积极治疗与舒适护理的患者的结局。这项回顾性分析使用了来自纽约市两家医疗中心的 65 岁及以上患者的电子健康记录数据,这些患者在 2020 年 3 月 5 日至 5 月 15 日期间入院。主要结局是舒适护理医嘱,次要结局包括死亡、姑息治疗咨询、治疗目标讨论、医嘱和呼吸机脱机。在 854 名患者中,214 名属于最年长的老年组(年龄≥85 岁),269 名属于中等年龄的老年组(年龄 75-84 岁),371 名属于年轻的老年组(年龄 65-74 岁)。在患有严重疾病的患者中,最年长的老年组更有可能选择舒适护理(45%比中等年龄的老年组 21%和年轻的老年组 6.8%),不太可能接受插管(17%比中等年龄的老年组 37%和年轻的老年组 44%),更有可能接受姑息治疗咨询,更有可能在入院时即为 DNR/DNI(60%比中等年龄的老年组 17%和年轻的老年组 9.3%),并且更有可能在入院期间死亡(65%比中等年龄的老年组 42%和年轻的老年组 21%)(所有 p 值均<0.001)。在所有 216 名接受插管的患者中,最年长的老年组的死亡率为 78%,而中等年龄的老年组为 66%,年轻的老年组为 36%(p<0.001)。因 COVID-19 入院的 85 岁及以上成年人更有可能放弃插管并接受基于舒适的治疗而死亡。无论选择插管与否,85 岁及以上的患者的预后明显比其他 65 岁以上的患者差。