有慢性阻塞性肺疾病（COPD）和间质性肺疾病（ILD）的非小细胞肺癌（NSCLC）患者接受根治性放疗的结果。
Outcomes of curative-intent radiotherapy in non-small cell lung cancer (NSCLC) patients with chronic obstructive pulmonary disease (COPD) and interstitial lung disease (ILD).
机构信息
Division of Medical Education, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom.
Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom; Division of Pharmacy and Optometry, School of Health Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom.
出版信息
Radiother Oncol. 2021 Jul;160:78-81. doi: 10.1016/j.radonc.2021.04.014. Epub 2021 Apr 24.
Outcomes of non-small cell lung cancer (NSCLC) patients with chronic obstructive pulmonary disease (COPD n = 587) and interstitial lung disease (ILD n = 34) treated with curative-intent radiotherapy were retrospectively investigated. Presence of ILD but not decreased forced expiratory volume in 1-second correlated with poor overall survival. Increased breathlessness and oxygen requirements after radiotherapy were observed in severe/very severe COPD and ILD.
回顾性研究了接受根治性放疗的慢性阻塞性肺疾病（COPD，n=587）和间质性肺疾病（ILD，n=34）的非小细胞肺癌（NSCLC）患者的结局。ILD 的存在而非 1 秒用力呼气量的降低与总生存不良相关。在 COPD 和 ILD 严重/极严重患者中，放疗后呼吸困难和氧气需求增加。
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