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间断缝合可预防腹部筋膜反复裂开:一项关于腹部切口裂开及其复发的危险因素以及手术修复技术的单中心队列比较回顾性分析

Interrupted sutures prevent recurrent abdominal fascial dehiscence: a comparative retrospective single center cohort analysis of risk factors of burst abdomen and its recurrence as well as surgical repair techniques.

作者信息

Mehdorn Matthias, Groos Linda, Kassahun Woubet, Jansen-Winkeln Boris, Gockel Ines, Moulla Yusef

机构信息

Department of Visceral, Transplant, Thoracic and Vascular Surgery, University Hospital of Leipzig, Liebigstraße 20, 04103, Leipzig, Germany.

出版信息

BMC Surg. 2021 Apr 26;21(1):208. doi: 10.1186/s12893-021-01219-x.

Abstract

BACKGROUND

Burst abdomen (BA) is a severe complication after abdominal surgery, which often requires urgent repair. However, evidence on surgical techniques to prevent burst abdomen recurrence (BAR) is scarce.

METHODS

We conducted a retrospective analysis of patients with BA comparing them to patients with superficial surgical site infections from the years 2015 to 2018. The data was retrieved from the institutional wound register. We analyzed risk factors for BA occurrence as well as its recurrence after BA repair and surgical closure techniques that would best prevent BAR.

RESULTS

We included 504 patients in the analysis, 111 of those suffered from BA. We found intestinal resection (OR 172.510; 22.195-1340.796, p < 0.001), liver cirrhosis (OR 4.788; 2.034-11.269, p < 0.001) and emergency surgery (OR 1.658; 1.050-2.617; p = 0.03) as well as postoperative delirium (OR 5.058; 1.349-18.965, p = 0.016) as the main predictor for developing BA. The main reason for BA was superficial surgical site infection (40.7%). 110 patients received operative revision of the abdominal fascial dehiscence and 108 were eligible for BAR analysis with 14 cases of BAR. Again, post-operative delirium was the patient-related predictor for BAR (OR 13.73; 95% CI 1.812-104-023, p = 0.011). The surgical technique of using interrupted sutures opposed to continuous sutures showed a preventive effect on BAR (OR 0.143, 95% CI 0.026-0,784, p = 0.025). The implantation of an absorbable IPOM mesh did not reduce BAR, but it did reduce the necessity of BAR revision significantly.

CONCLUSION

The use of interrupted sutures together with the implantation of an intraabdominal mesh in burst abdomen repair helps to reduce BAR and the need for additional revision surgeries.

摘要

背景

腹部切口裂开是腹部手术后的一种严重并发症,常需紧急修复。然而,关于预防腹部切口裂开复发(BAR)的手术技术的证据很少。

方法

我们对2015年至2018年期间腹部切口裂开患者与浅表手术部位感染患者进行了回顾性分析。数据从机构伤口登记处获取。我们分析了腹部切口裂开发生的危险因素、腹部切口裂开修复后的复发情况以及最能预防腹部切口裂开复发的手术闭合技术。

结果

我们纳入了504例患者进行分析,其中111例患有腹部切口裂开。我们发现肠切除术(OR 172.510;22.195 - 1340.796,p < 0.001)、肝硬化(OR 4.788;2.034 - 11.269,p < 0.001)、急诊手术(OR 1.658;1.050 - 2.617;p = 0.03)以及术后谵妄(OR 5.058;1.349 - 18.965,p = 0.016)是发生腹部切口裂开的主要预测因素。腹部切口裂开的主要原因是浅表手术部位感染(40.7%)。110例患者接受了腹部筋膜裂开的手术修复,108例符合腹部切口裂开复发分析条件,其中14例发生腹部切口裂开复发。同样,术后谵妄是与患者相关的腹部切口裂开复发预测因素(OR 13.73;95% CI 1.812 - 104.023,p = 0.011)。与连续缝合相比,采用间断缝合的手术技术对腹部切口裂开复发有预防作用(OR 0.143,95% CI 0.026 - 0.784,p = 0.025)。植入可吸收的腹腔内补片不能降低腹部切口裂开复发率,但能显著降低腹部切口裂开复发修复的必要性。

结论

在腹部切口裂开修复中,使用间断缝合并植入腹腔内补片有助于降低腹部切口裂开复发率以及减少额外修复手术的需求。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0458/8074409/f59a2d2649e3/12893_2021_1219_Fig1_HTML.jpg

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