Department of Neurology, Washington University School of Medicine, 660 South Euclid Avenue, Campus Box 8111, St Louis, MO 63110-1093, USA; Department of Pediatrics, Washington University School of Medicine, 660 South Euclid Avenue, Campus Box 8116, St Louis, MO 63110-1093, USA; Department of Radiology, Washington University School of Medicine, 660 South Euclid Avenue, Campus Box 8131, St Louis, MO 63110-1093, USA.
Department of Neurology, Washington University School of Medicine, 660 South Euclid Avenue, Campus Box 8111, St Louis, MO 63110-1093, USA; Department of Pediatrics, Washington University School of Medicine, 660 South Euclid Avenue, Campus Box 8116, St Louis, MO 63110-1093, USA; Department of Radiology, Washington University School of Medicine, 660 South Euclid Avenue, Campus Box 8131, St Louis, MO 63110-1093, USA.
Magn Reson Imaging Clin N Am. 2021 May;29(2):185-193. doi: 10.1016/j.mric.2021.01.004.
Diffusion magnetic resonance imaging (MRI) offers a wealth of information regarding the neonatal brain. Diffusion anisotropy values reflect changes in the microstructure that accompany early maturation of white and gray matter. In term neonates with neonatal encephalopathy, diffusion imaging provides a useful means of assessing brain injury during the first week of life. In preterm neonates, measures of white matter anisotropy provide information on the nature and extent of white matter disruption. Subsequently, diffusion MRI plays an important role in illuminating fundamental elements of brain development and fulfilling the clinical need to develop prognostic indicators for term and preterm infants.
弥散磁共振成像（MRI）为新生儿脑提供了丰富的信息。弥散各向异性值反映了伴随白质和灰质早期成熟的微观结构变化。对于患有新生儿脑病的足月新生儿，弥散成像为评估生命第一周的脑损伤提供了有用的手段。对于早产儿，白质各向异性的测量值提供了有关白质破坏性质和程度的信息。随后，弥散 MRI 在阐明脑发育的基本要素以及满足为足月和早产儿开发预后指标的临床需求方面发挥着重要作用。
