Department of Neonatology, Sri Ramachandra Institute of Higher Education & Research, Porur, Chennai, India.
Department of Microbiology, Sri Ramachandra Institute of Higher Education & Research, Porur, Chennai, India.
Indian J Med Microbiol. 2021 Jul;39(3):367-369. doi: 10.1016/j.ijmmb.2021.03.025. Epub 2021 Apr 24.
Clinical profile of extreme preterm neonates and more so, of microprimies with birth weight < 800 g is not studied till now. Our article elaborates the profile of 5 microprimies with C.auris sepsis and review of literature. The mean gestational age and birth weight were 26 weeks ± 5 days and 709 ± 64 g respectively. Mortality was 80%. The organism was susceptible to micafungin, voriconazole but was resistant to fluconazole and amphotericin. Among the 5 babies, one had organ involvement in the form of cardiac vegetation. Early identification and optimal choice of drug are crucial for better survival in C.auris sepsis.
目前尚未对极低出生体重儿，尤其是出生体重<800g 的极早产儿的临床特征进行研究。我们的文章阐述了 5 例患有耳念珠菌血症的极早产儿的临床特征，并对文献进行了回顾。平均胎龄和出生体重分别为 26 周±5 天和 709±64g。死亡率为 80%。该生物体对米卡芬净、伏立康唑敏感，但对氟康唑和两性霉素 B 耐药。在这 5 名婴儿中，有 1 名出现了心脏赘生物的器官受累。在耳念珠菌血症中，早期识别和选择最佳药物对提高生存率至关重要。
