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Caspase-1: an important player and possible target for repair of the blood-brain barrier underlying neurodegeneration.

作者信息

Rand Daniel, Cooper Itzik

机构信息

The Joseph Sagol Neuroscience Center, Sheba Medical Center, Ramat-Gan; Sackler Faculty of Medicine, Tel-Aviv University, Tel Aviv, Israel.

The Joseph Sagol Neuroscience Center, Sheba Medical Center, Ramat-Gan; School of Psychology, Interdisciplinary Center (IDC), Herzliya; The Nehemia Rubin Excellence in Biomedical Research - The TELEM Program, Sheba Medical Center, Tel-Hashomer, Israel.

出版信息

Neural Regen Res. 2021 Dec;16(12):2390-2392. doi: 10.4103/1673-5374.313031.

DOI:10.4103/1673-5374.313031
PMID:33907012
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8374582/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/babb/8374582/608b9dab9802/NRR-16-2390-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/babb/8374582/608b9dab9802/NRR-16-2390-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/babb/8374582/608b9dab9802/NRR-16-2390-g001.jpg

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J Neuroinflammation. 2020 Sep 9;17(1):267. doi: 10.1186/s12974-020-01927-w.
2
Levels of caspase-1 in cerebrospinal fluid of patients with traumatic brain injury: correlation with intracranial pressure and outcome.颅脑创伤患者脑脊液中半胱氨酸天冬氨酸蛋白酶-1 水平:与颅内压和预后的相关性。
J Neurosurg. 2020 May 1;134(5):1644-1649. doi: 10.3171/2020.2.JNS193079. Print 2021 May 1.
3
Caspase-1 inhibition prevents neuronal death by targeting the canonical inflammasome pathway of pyroptosis in a murine model of cerebral ischemia.
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J Pharmacol Exp Ther. 2024 Jan 17;388(2):301-312. doi: 10.1124/jpet.123.001836.
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Nutrients. 2022 Nov 30;14(23):5091. doi: 10.3390/nu14235091.
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