Department of Anesthesiology, Harrison International Peace Hospital, Hebei Medical University, Hengshui, Hebei Province, China.
Medicine (Baltimore). 2021 Apr 30;100(17):e25651. doi: 10.1097/MD.0000000000025651.
Dexamethasone has been widely used in brachial plexus block to enhance the effects of brachial plexus block. However, the clinical findings are not consistent with the dosage of dexamethasone prolonging local anesthetic nerve block. Therefore, the purpose of this study was to explore the effects of different doses of dexamethasone as local anesthetic adjuvant on brachial plexus block through network meta-analysis.
We searched PubMed, Web of Science, Cochrane Library, and Embase databases to collect all randomized controlled trials (RCTs) of different doses of dexamethasone as local anesthetic adjuvant on brachial plexus block until March 2021. Two researchers then independently screened articles, extracted data, and evaluated the quality of selected literatures. All data was processed by Stata 14.0 and WinBUGS 1.4.3.software.
The results of this meta-analysis will be submitted to a peer-reviewed journal for publication.
Our study is expected to provide high-quality evidence-based medicine advice for the effects of different doses of dexamethasone as local anesthetic adjuvant on brachial plexus block.
Ethical approval was not required for this study. The systematic review will be published in a peer-reviewed journal, presented at conferences, and shared on social media platforms.
DOI 10.17605/OSF.IO/PZ5WR.
地塞米松已广泛应用于臂丛神经阻滞以增强臂丛神经阻滞的效果。然而，临床发现地塞米松剂量与延长局部麻醉神经阻滞的效果并不一致。因此，本研究旨在通过网络荟萃分析探讨不同剂量地塞米松作为局部麻醉剂佐剂对臂丛神经阻滞的影响。
我们检索了 PubMed、Web of Science、Cochrane Library 和 Embase 数据库，收集了截至 2021 年 3 月所有关于不同剂量地塞米松作为局部麻醉剂佐剂用于臂丛神经阻滞的随机对照试验（RCT）。然后由两名研究人员独立筛选文章、提取数据并评估所选文献的质量。所有数据均由 Stata 14.0 和 WinBUGS 1.4.3 软件处理。
本荟萃分析的结果将提交给同行评议的期刊发表。
我们的研究有望为不同剂量地塞米松作为局部麻醉剂佐剂对臂丛神经阻滞的效果提供高质量的循证医学建议。
本研究无需伦理批准。系统评价将发表在同行评议的期刊上，并在会议上展示，并在社交媒体平台上分享。
OSF 注册号：DOI 10.17605/OSF.IO/PZ5WR。
