Yuan Sheng, Shi Ying, Li Minmin, Hu Xiaojun, Bai Ruhai
Department of New Medicine and Needle Pricking, The First Affiliated Hospital of Jinan University, Guangzhou, Guangdong, People's Republic of China.
Department of Surgery, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China.
Int J Gen Med. 2021 Apr 20;14:1413-1420. doi: 10.2147/IJGM.S305358. eCollection 2021.
Urinary tract infection (UTI) is the second-most-common type of infection in China. This study aimed to determine the long-term trends in the incidence of UTI in Mainland China between 1990 and 2019.
Data were extracted from the Global Burden of Disease Study 2019 and were analyzed with the age-period-cohort framework.
The net drift in the incidence of UTI was -0.37% (95% CI: -0.40%, -0.35%) in males and -0.25% (95% CI: -0.29%, -0.20%) in females. For males, the local drift was lower than 0 (P<0.05) among those younger than 90 years. For females, the local drift was lower than 0 (P<0.05) among those younger than 60 years and higher than 0 (P<0.05) in those aged 65-79 years. In the same birth cohort, the incidence of UTI was higher in females than in males in all age groups (P<0.05). The period relative risk (RR) showed a decreasing pattern after 2005 in both sexes. The cohort RR showed a downward trend of the birth cohort after 1905 for males and 1960 for females.
The incidence has increased significantly among older females over the past 30 years. It is necessary to develop a comprehensive intervention plan for reproductive health services covering females and males of all ages.
尿路感染（UTI）是中国第二常见的感染类型。本研究旨在确定1990年至2019年中国大陆UTI发病率的长期趋势。
数据取自《2019年全球疾病负担研究》，并采用年龄-时期-队列框架进行分析。
男性UTI发病率的净变化率为-0.37%（95%CI：-0.40%，-0.35%），女性为-0.25%（95%CI：-0.29%，-0.20%）。对于男性，90岁以下人群的局部变化率低于0（P<0.05）。对于女性，60岁以下人群的局部变化率低于0（P<0.05），65-79岁人群的局部变化率高于0（P<0.05）。在同一年龄队列中，各年龄组女性的UTI发病率均高于男性（P<0.05）。2005年后，两性的时期相对风险（RR）均呈下降趋势。男性1905年后、女性1960年后出生队列的队列RR呈下降趋势。
在过去30年中，老年女性的发病率显著增加。有必要制定一项涵盖所有年龄段男性和女性的生殖健康服务综合干预计划。
