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与家庭照顾者负担和抑郁相关的神经精神症状。

Neuropsychiatric symptoms associated with family caregiver burden and depression.

作者信息

Delfino Lais Lopes, Komatsu Ricardo Shoiti, Komatsu Caroline, Neri Anita Liberalesso, Cachioni Meire

机构信息

School of Medical Sciences, Universidade Estadual de Campinas - Campinas, SP, Brazil.

Geriatrics and Gerontology Discipline, Faculdade de Medicina de Marília - Marília, SP, Brazil.

出版信息

Dement Neuropsychol. 2021 Jan-Mar;15(1):128-135. doi: 10.1590/1980-57642021dn15-010014.

DOI:10.1590/1980-57642021dn15-010014
PMID:33907606
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8049583/
Abstract

UNLABELLED

Alzheimer's disease (AD) is a progressive and degenerative condition affecting several cognitive areas, with a decline in functional abilities and behavioral changes.

OBJECTIVE

To investigate the association between neuropsychiatric symptoms in older adults with AD and caregiver burden and depression.

METHODS

A total of 134 family caregivers of older people diagnosed with AD answered a questionnaire with sociodemographic data and questions concerning the care context, neuropsychiatric symptoms, caregiver burden, and depressive symptoms.

RESULTS

Results revealed that 95% of older adults had at least one neuropsychiatric symptom, with the most common being: apathy, anxiety, and depression. Among the 12 neuropsychiatric symptoms investigated, 10 were significantly associated with caregiver burden, while 8 showed significant correlations with depressive symptoms.

CONCLUSIONS

Neuropsychiatric symptoms were related to caregiver burden and depressive symptoms. In addition to the older adult with AD, the caregiver should receive care and guidance from the health team to continue performing quality work.

摘要

未标注

阿尔茨海默病(AD)是一种进行性退行性疾病,影响多个认知领域,伴有功能能力下降和行为改变。

目的

探讨患有AD的老年人的神经精神症状与照顾者负担及抑郁之间的关联。

方法

134名被诊断患有AD的老年人的家庭照顾者回答了一份包含社会人口学数据以及关于照顾情况、神经精神症状、照顾者负担和抑郁症状问题的问卷。

结果

结果显示,95%的老年人至少有一种神经精神症状,最常见的是:冷漠、焦虑和抑郁。在所调查的12种神经精神症状中,10种与照顾者负担显著相关,而8种与抑郁症状显著相关。

结论

神经精神症状与照顾者负担和抑郁症状相关。除了患有AD的老年人外,照顾者也应接受健康团队的护理和指导,以便继续提供高质量的照顾。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/06ca/8049583/b3ed955a1e7c/1980-5764-dn-15-01-0128-gf01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/06ca/8049583/b3ed955a1e7c/1980-5764-dn-15-01-0128-gf01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/06ca/8049583/b3ed955a1e7c/1980-5764-dn-15-01-0128-gf01.jpg

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本文引用的文献

1
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2
Informal caregiving for dementia patients: the contribution of patient characteristics and behaviours to caregiver burden.痴呆症患者的非正式护理:患者特征和行为对护理人员负担的影响。
Age Ageing. 2019 Dec 1;49(1):52-56. doi: 10.1093/ageing/afz128.
3
Neuropsychiatric symptoms and executive function impairments in Alzheimer's disease and vascular dementia: The role of subcortical circuits.
照顾痴呆症患者对非正式照顾者的影响:家庭功能、负担和倦怠。
J Clin Psychol Med Settings. 2025 Jun;32(2):325-335. doi: 10.1007/s10880-024-10052-2. Epub 2024 Oct 25.
4
Emotion regulation in people living with dementia and their spouses: the role of neuropsychiatric symptoms.痴呆症患者及其配偶的情绪调节:神经精神症状的作用。
Aging Ment Health. 2024 Dec;28(12):1733-1740. doi: 10.1080/13607863.2024.2367038. Epub 2024 Jun 28.
5
Comparing clinico-demographics and neuropsychiatric symptoms for immigrant and non-immigrant aged care residents living with dementia: a retrospective cross-sectional study from an Australian dementia-specific support service.比较移民和非移民老年痴呆症患者的临床人口统计学和神经精神症状:来自澳大利亚专门的痴呆症支持服务的回顾性横断面研究。
BMC Geriatr. 2023 Nov 10;23(1):729. doi: 10.1186/s12877-023-04447-3.
6
Emotion Regulation in Dementia Caregiving: The Role of Neuropsychiatric Symptoms and Attachment Orientation.痴呆症照护中的情绪调节:神经精神症状和依恋取向的作用。
J Geriatr Psychiatry Neurol. 2024 Mar;37(2):146-156. doi: 10.1177/08919887231195228. Epub 2023 Aug 4.
7
An Update on Apathy in Alzheimer's Disease.阿尔茨海默病中淡漠症状的最新进展
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Int Psychogeriatr. 2024 Apr;36(4):251-262. doi: 10.1017/S104161022200103X. Epub 2023 Mar 6.
阿尔茨海默病和血管性痴呆中的神经精神症状与执行功能障碍:皮质下回路的作用
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5
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9
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