Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Australia.
School of Exercise and Nutrition Sciences, Queensland University of Technology, Brisbane, Australia.
J Neurooncol. 2021 May;153(1):1-14. doi: 10.1007/s11060-021-03745-3. Epub 2021 Apr 28.
The aims of this systematic review were to: (1) describe physical activity (PA) levels following diagnosis of primary brain cancer, (2) determine the relationship between PA levels and health outcomes, and (3) assess the effect of participating in an exercise intervention on health outcomes following a diagnosis of brain cancer.
PubMed, EMBASE, Scopus and CINAHL were searched for relevant articles published prior to May 1, 2020. Studies reporting levels of PA, the relationship between PA and health outcomes, and exercise interventions conducted in adults with brain cancer were eligible. The search strategy included terms relating to primary brain cancer, physical activity, and exercise. Two independent reviewers assessed articles for eligibility and methodological quality (according to Joanna Briggs Institute Critical Appraisal Tools). Descriptive statistics were used to present relevant data and outcomes.
15 studies were eligible for inclusion. Most adults with brain cancer were insufficiently active from diagnosis through to post-treatment. Higher levels of PA were associated with lower severity of brain cancer specific concerns and higher quality of life. Preliminary evidence suggests that exercise is safe, feasible and potentially beneficial to brain cancer symptom severity and interference, aerobic capacity, body composition and PA levels. However, the level of evidence to support these findings is graded as weak.
Evidence suggests that it is likely appropriate to promote those with brain cancer to be as physically active as possible. The need or ability of those with brain cancer to meet current PA guidelines promoted to all people with cancer remains unclear.
本系统评价的目的是：（1）描述原发性脑癌诊断后的体力活动（PA）水平，（2）确定 PA 水平与健康结果之间的关系，以及（3）评估在脑癌诊断后参加运动干预对健康结果的影响。
检索了 PubMed、EMBASE、Scopus 和 CINAHL 数据库，以获取截至 2020 年 5 月 1 日之前发表的相关文章。符合条件的研究报告了 PA 水平、PA 与健康结果之间的关系以及针对脑癌成人开展的运动干预。搜索策略包括与原发性脑癌、体力活动和运动相关的术语。两名独立的评审员评估了文章的入选资格和方法学质量（根据 Joanna Briggs 研究所的批判性评估工具）。使用描述性统计来呈现相关数据和结果。
有 15 项研究符合入选标准。大多数脑癌患者从诊断到治疗后都没有足够的体力活动。较高的 PA 水平与较低的脑癌特异性担忧严重程度和较高的生活质量相关。初步证据表明，运动是安全、可行的，可能对脑癌症状严重程度和干扰、有氧运动能力、身体成分和 PA 水平有益。然而，支持这些发现的证据水平被评为较弱。
有证据表明，鼓励脑癌患者尽可能多地进行身体活动可能是合适的。对于那些患有脑癌的人来说，需要或能够达到目前针对所有癌症患者推荐的 PA 指南仍不清楚。
