Department of Pharmacy and Therapeutics, School of Pharmacy, University of Pittsburgh, Pittsburgh, PA.
Division of General Internal Medicine, School of Medicine, University of Pittsburgh, Pittsburgh, PA.
J Manag Care Spec Pharm. 2021 May;27(5):565-573. doi: 10.18553/jmcp.2021.27.5.565.
Medicare Part B pharmaceutical spending has increased rapidly, more than doubling in 2006-2017. Yet, it is unclear whether this increase was driven by increased utilization or increased cost per claim. To evaluate the relative impact of changes in drug utilization and cost per claim on changes in Medicare Part B pharmaceutical spending in 2008-2016 overall, by drug type (specialty and nonspecialty) and therapeutic category. In this retrospective descriptive study, we extracted all claims in 2008-2016 for separately payable Part B drugs from a 5% random sample of Medicare beneficiaries. Our study included 3 outcomes calculated annually for all included drugs: (1) spending, defined as the sum of total payments; (2) utilization, defined as total number of claims; and (3) cost per claim, defined as spending divided by the number of claims. Estimates of spending and utilization were expressed per beneficiary-year. Spending and cost per claim were adjusted for inflation. For each outcome, we calculated relative changes in 2008-2016. We repeated analyses stratifying by drug type (specialty and nonspecialty) and therapeutic class. Pharmaceutical spending in Medicare Part B increased by 34% from 2008-2016, driven by a 53% increase in the cost per claim. Utilization decreased by 12%. Spending on specialty drugs increased by 56%, driven by a 48% increase in the cost per claim and a 6% utilization increase. Spending on nonspecialty drugs decreased by 32% driven by an 18% reduction in the cost per claim and a 17% reduction in utilization. Spending on ophthalmic preparations increased by 281%, driven by a 238% utilization increase and a 13% increase in the cost per claim. Spending on antiarthritic and immunologic agents increased by 159%, driven by a 117% increase in the cost per claim and a 19% utilization increase. Medicare Part B pharmaceutical spending grew in recent years, despite decreased utilization, driven by an overall increase in the cost per claim. This was a product of rising drug prices and increased utilization of more expensive specialty drugs. These findings support the development of policies that aim to spur competition and control price growth of provider-administered drugs. The authors acknowledge funding from the Myers Family Foundation. Hernandez was funded by the National Heart, Lung and Blood Institute (grant number K01HL142847). Shrank is an employee of Humana. Good is an employee of the UPMC Health Plan Insurance Services Division. There are no other potential conflicts of interest to disclose.
医疗保险 B 部分药品支出迅速增加,2006 年至 2017 年翻了一番多。然而,尚不清楚这种增长是由利用率增加还是每次索赔的成本增加驱动的。为了评估 2008-2016 年期间药物利用率和每次索赔成本变化对医疗保险 B 部分药品支出变化的相对影响,我们按药物类型(专科药物和非专科药物)和治疗类别进行了评估。在这项回顾性描述性研究中,我们从医疗保险受益人的 5%随机样本中提取了 2008-2016 年所有可单独支付的 B 部分药物的所有索赔。我们的研究包括为所有纳入药物计算的 3 个年度结果:(1)支出,定义为总付款额;(2)利用率,定义为索赔总数;(3)每次索赔的成本,定义为支出除以索赔数量。受益人的年支出和利用率进行了估计。支出和每次索赔的成本均根据通货膨胀进行了调整。对于每个结果,我们计算了 2008-2016 年的相对变化。我们按药物类型(专科药物和非专科药物)和治疗类别对分析进行了分层。医疗保险 B 部分药品支出从 2008 年至 2016 年增加了 34%,这主要是由于每次索赔成本增加了 53%。利用率下降了 12%。专科药物支出增加了 56%,这主要是由于每次索赔成本增加了 48%,利用率增加了 6%。非专科药物支出下降了 32%,这主要是由于每次索赔成本下降了 18%,利用率下降了 17%。眼科制剂支出增加了 281%,这主要是由于利用率增加了 238%,每次索赔成本增加了 13%。抗关节炎和免疫制剂支出增加了 159%,这主要是由于每次索赔成本增加了 117%,利用率增加了 19%。近年来,尽管利用率下降,但医疗保险 B 部分药品支出仍在增长,这主要是由于每次索赔的成本总体上有所增加。这是由于药品价格上涨和更昂贵的专科药物利用率增加所致。这些发现支持制定旨在刺激竞争和控制供应商管理药物价格增长的政策。作者感谢 Myers 家族基金会的资助。Hernandez 得到了美国国立卫生研究院(赠款号 K01HL142847)的资助。Shrank 是 Humana 的员工。Good 是 UPMC Health Plan Insurance Services Division 的员工。没有其他潜在的利益冲突需要披露。