University of Yaounde 1, Cameroon, and Cameroon Bioethics Initiative (CAMBIN), Simbok, Yaounde, CAMEROON.
Indian J Med Ethics. 2021 Apr-Jun;VI(2):1-12. doi: 10.20529/IJME.2021.028.
On January 14, 2021, a WHO Ad Hoc expert group published an article in the highly influential The New England Journal of Medicine, titled: "Placebo-Controlled Trials of Covid-19 Vaccines - Why We Still Need Them" justifying the use of placebo in further trials of Covid-19 vaccines, even after purported efficacious vaccines have become available. Medical research involving human beings ought to conform strictly to principles, rules and procedures established since the Nuremberg Code (1947), especially as elaborated in the Declaration of Helsinki (2013) and the WHO/CIOMS Guidelines (2016). The NEJM article forms part of an observable trend of moral backsliding that needs to be recorded. In this paper, considering traditional medical research ethics under the impact of the Covid-19 pandemic and its ramifications and effects, and with a particular focus on the highly vulnerable populations and countries of sub-Saharan Africa, I make some relevant remarks. My arguments here are anchored in my observations as a moral philosopher though limited by my lack of expertise in any of the branches of medical science.
2021 年 1 月 14 日,世界卫生组织一个特设专家组在极有影响力的《新英格兰医学杂志》上发表了一篇文章,题为:“新冠病毒疫苗的安慰剂对照试验——为什么我们仍然需要它们”,为在据称有效的疫苗问世后,在新冠病毒疫苗的进一步试验中使用安慰剂辩护。涉及人类的医学研究理应严格遵守自纽伦堡法典(1947 年)以来制定的原则、规则和程序,尤其是《赫尔辛基宣言》(2013 年)和世界卫生组织/医学研究伦理委员会(2016 年)的详细阐述。《新英格兰医学杂志》这篇文章构成了需要记录的明显道德倒退趋势的一部分。在本文中,我考虑了新冠大流行及其影响下传统医学研究伦理,特别关注特别脆弱的人群和撒哈拉以南非洲国家,提出了一些相关看法。我的观点基于我作为道德哲学家的观察,但受到我在医学科学任何分支都缺乏专业知识的限制。