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沙特阿拉伯东部省份消化系统恶性肿瘤:158例患者分析

Digestive system malignancies in the eastern province of Saudi Arabia: an analysis of 158 patients.

作者信息

al Quorain A, Satti M B, al Idrissi H Y, Ibrahim E M, al Freihi H, al-Hamdan A R, al Dossary J, Abdel Hadi M

机构信息

College of Medicine & Medical Sciences, King Faisal University, Dammam, Saudi Arabia.

出版信息

Cancer Detect Prev. 1988;11(3-6):331-6.

PMID:3390855
Abstract

Retrospective evaluation of 158 patients with digestive system neoplasms was carried out. The disease pattern was compared to that noted in other parts of Arabia, other Middle East countries, Africa, and the West. An attempt was made to analyze potential aetiological factors in the Saudi population. At all cancer sites of the digestive system the male to female ratio was 3:1. Generally more younger patients with advanced cancer were encountered than reported in series from the Western hemisphere. The poor results of therapy were generally attributed to the advanced stage at presentation. The high frequency of GIT cancer and in particular the apparently rising incidence rate of colorectal cancer was attributed to dietary habits and the changing lifestyle of the population. Hepatitis B viral infection was the likely cause of primary hepatocellular cancer (PHC) although dietary factors could not be ruled out. Schistosomiasis was found not to play a role in the causation of either PHC or colorectal cancer.

摘要

对158例消化系统肿瘤患者进行了回顾性评估。将该疾病模式与阿拉伯半岛其他地区、其他中东国家、非洲和西方所记录的情况进行了比较。尝试分析沙特人群中潜在的病因因素。在消化系统的所有癌症部位,男女比例为3:1。总体而言,与西半球系列报道相比,遇到的晚期癌症年轻患者更多。治疗效果不佳通常归因于就诊时的晚期阶段。胃肠道癌症的高发病率,尤其是结直肠癌明显上升的发病率,归因于饮食习惯和人群生活方式的改变。乙型肝炎病毒感染可能是原发性肝细胞癌(PHC)的病因,尽管不能排除饮食因素。发现血吸虫病在原发性肝细胞癌或结直肠癌的病因中不起作用。

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