Department of Systems Physiology, Graduate School of Medicine, University of the Ryukyus, 207 Uehara, Nishihara, Okinawa, 903-0215, Japan.
Department of Urology, Graduate School of Medicine, University of the Ryukyus, Okinawa, Japan.
Int Urol Nephrol. 2021 Aug;53(8):1497-1505. doi: 10.1007/s11255-021-02867-x. Epub 2021 Apr 28.
To evaluate the effect of a mobile digital intervention on voiding patterns, we performed 24-h voided volume monitoring in individuals with metabolic disorders.
Participants with metabolic disorders were grouped into either the intervention group (n = 17), who had access to a smartphone app (CARADA), or the non-intervention group (n = 11), who did not. Urine monitoring was conducted for 24 h using a novel digital self-health monitoring system for urine excretion (s-HMSU). Body weight, abdominal circumference, blood pressure, and biomarkers were measured.
Physical findings and blood test results at baseline and 6 months indicated no significant between-group differences. Night-time frequency did not change between baseline and 6 months in the intervention group but significantly worsened at 6 months in the non-intervention group, as compared to baseline (1.0 ± 0.7 vs. 1.5 ± 0.5, p < 0.05). The change in night-time frequency over 6 months did not differ between the intervention and non-intervention groups. Furthermore, the change in hours of undisturbed sleep over 6 months did not differ between the two groups. However, compared with baseline, nocturnal polyuria index tended to worsen at 6 months in the non-intervention group.
Our study results suggest that mobile digital intervention might be useful for behavioral therapy to improve night-time frequency and urine production and that s-HMSU might be beneficial for confirming the prevention of progress in individuals with metabolic disorders, which can aid in modifying lifestyle.
为了评估移动数字干预对排尿模式的影响,我们对代谢紊乱患者进行了 24 小时排尿量监测。
将代谢紊乱患者分为干预组(n=17)和非干预组(n=11)。干预组可使用智能手机应用程序(CARADA),而非干预组则不能。使用新型数字尿液自我监测系统(s-HMSU)进行 24 小时尿液监测。测量体重、腹围、血压和生物标志物。
基线和 6 个月时的体格检查和血液检查结果表明两组间无显著差异。与基线相比,干预组夜间排尿频率在 6 个月内没有变化,但非干预组夜间排尿频率在 6 个月内明显恶化(1.0±0.7 比 1.5±0.5,p<0.05)。两组间夜间排尿频率的变化在 6 个月内无差异。此外,两组间 6 个月内未受干扰睡眠时间的变化无差异。然而,与基线相比,非干预组夜间多尿指数在 6 个月时趋于恶化。
我们的研究结果表明,移动数字干预可能有助于改善夜间排尿频率和尿液生成的行为治疗,s-HMSU 可能有助于确认代谢紊乱患者进展的预防,从而有助于改变生活方式。