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COVID-19 肺炎与已知软骨肉瘤患者肺部转移同时发生:一例报告。

Simultaneous development of COVID-19 pneumonia and pulmonary metastasis in a known case of chondrosarcoma: a case report.

机构信息

Department of Radiation Oncology, Shahid Beheshti University of Medical Sciences, Shohada-e Tajrish Hospital, Shahrdari St, 1989934148, Tehran, Iran.

Department of Radiology, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

出版信息

J Med Case Rep. 2021 Apr 28;15(1):218. doi: 10.1186/s13256-021-02753-1.

Abstract

BACKGROUND

The outbreak of coronavirus disease 2019 (COVID-19) started in December 2020, and is a global problem now. There are several sets of established data regarding computed tomography (CT) findings in COVID-19 pneumonia with many differential diagnoses. During the early days of the pandemic, there was little data regarding lung CT features of COVID-19 in a cancer patient. In this paper, we described a rare case of simultaneous presentation of COVID-19 with pulmonary metastasis.

CASE PRESENTATION

A Persian patient with a history of chondrosarcoma presented to our clinic during the COVID-19 pandemic with a new-onset cough. He had experienced no recurrence during previous follow-up visits. Chest CT scan revealed numerous bilateral small peripheral and perilymphatic pulmonary nodules, unilateral ground-glass patch, and nodular interlobular septal thickening. Biopsy of the pulmonary nodules established pulmonary metastasis of chondrosarcoma origin, and pharyngeal reverse transcription polymerase chain reaction (RT-PCR) was positive for COVID-19.

CONCLUSION

Pulmonary metastasis should be considered as a differential diagnosis of COVID-19 features in cancer patients in the pandemic era.

摘要

背景

2019 年冠状病毒病(COVID-19)疫情于 2020 年 12 月爆发,目前已成为全球性问题。COVID-19 肺炎的 CT 表现已有多套确立的数据集,且有许多鉴别诊断。在疫情早期,有关癌症患者 COVID-19 肺部 CT 特征的数据很少。本文描述了一例 COVID-19 与肺转移同时发生的罕见病例。

病例介绍

一名有软骨肉瘤病史的波斯患者在 COVID-19 大流行期间因新发咳嗽就诊于我院。在之前的随访中,他没有复发。胸部 CT 扫描显示双侧多个小周边和肺周肺结节、单侧磨玻璃样斑片和结节性小叶间隔增厚。肺结节活检确立了软骨肉瘤来源的肺转移,咽拭子逆转录聚合酶链反应(RT-PCR)COVID-19 阳性。

结论

在大流行时代,对于癌症患者 COVID-19 特征,应考虑肺转移作为鉴别诊断。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5597/8082872/978cf9ff28ba/13256_2021_2753_Fig1_HTML.jpg

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