Dapoigny M, Trolese J F, Bommelaer G, Tournut R
Groupe de Recherche en Epidemiologie, Pathologie Digestive et Nutrition, Hotel Dieu, Clermont-Ferrand, France.
Dig Dis Sci. 1988 Aug;33(8):1007-12. doi: 10.1007/BF01535998.
The tip of an intraluminal probe was positioned in the cecum, and before and after a standard meal (greater than 800 kcal), the rapid myoelectrical activity of the right, the left, and the rectosigmoid colon in six healthy subjects was recorded. In each colonic site, we recorded two different patterns of spike bursts: Short spike bursts and long spike bursts, as previously described. We observed no difference in either the duration or the amplitude of the two kinds of spike bursts among the three different parts of the colon. Before the meal, the number of long spike bursts was lower in the right than in the left colon (P less than 0.01) and than in the rectosigmoid (P less than 0.01). After the meal, a significant activity increase in long spike bursts lasted 20 min in the right colon (P less than 0.001), 100 min in the left colon, and in the rectosigmoid (P less than 0.001-P less than 0.05). This activity was always significantly less intense in the right colon than in the two other sites (P less than 0.001-P less than 0.01) and was less marked in the left colon than in the rectosigmoid (P 0.01-P less than 0.05). The short spike burst activity remained unchanged. These results provide evidence for the heterogeneity of motility in the different parts of the colon, with a relative hypomotility of the right colon compared to the left colon and the rectosigmoid in the healthy human.
将腔内探头的尖端置于盲肠中，在六名健康受试者摄入标准餐（大于800千卡）前后，记录右半结肠、左半结肠和直肠乙状结肠的快速肌电活动。在每个结肠部位，我们记录了两种不同模式的尖峰爆发：如前所述的短尖峰爆发和长尖峰爆发。我们观察到在结肠的三个不同部位，这两种尖峰爆发的持续时间和幅度均无差异。餐前，右半结肠的长尖峰爆发数量低于左半结肠（P<0.01）和直肠乙状结肠（P<0.01）。餐后，右半结肠长尖峰爆发的显著活动增加持续20分钟（P<0.001），左半结肠和直肠乙状结肠持续100分钟（P<0.001 - P<0.05）。右半结肠的这种活动强度始终显著低于其他两个部位（P<0.001 - P<0.01），左半结肠的活动比直肠乙状结肠的活动更不明显（P 0.01 - P<0.05）。短尖峰爆发活动保持不变。这些结果为结肠不同部位运动的异质性提供了证据，在健康人中，右半结肠相对于左半结肠和直肠乙状结肠存在相对运动减弱。
