Deshpande Swanit Hemant, Narkhede Vishal, Eswaravaka Sai Krishna, Pandya Jayashri Sanjay
General Surgery, BYL Nair Charitable Hospital, Mumbai, Maharashtra, India.
Department of General Surgery, Topiwala National Medical College, Mumbai, Maharashtra, India.
BMJ Case Rep. 2021 Apr 28;14(4):e240621. doi: 10.1136/bcr-2020-240621.
Malignant melanoma of the anal canal is a rare and aggressive tumour associated with significant mortality. Early diagnosis and early curative surgical resection have shown to offer a survival advantage. We present a case of 53-year-old woman, who was accidentally diagnosed to have a localised lesion of malignant melanoma of the anal canal on histopathology report of the specimen of haemorrhoidectomy done for thrombosed external haemorrhoids. She refused any form of treatment and did not return for follow-up. Two years after the initial diagnosis, she presented with intestinal obstruction. The malignant melanoma had become advanced with multiple metastases to the lungs, the liver, the peritoneum and the spine. The patient underwent a diverting loop ileostomy. At the time of surgery, it was found that the primary malignant melanoma of anal canal had contiguously involved the entire large intestine up to the ileocaecal junction and hence transverse colostomy could not be done.
肛管恶性黑色素瘤是一种罕见且侵袭性强的肿瘤,死亡率很高。早期诊断和早期根治性手术切除已显示出具有生存优势。我们报告一例53岁女性病例,她因血栓性外痔行痔切除术,术后标本的组织病理学报告意外诊断为肛管恶性黑色素瘤局限性病变。她拒绝任何形式的治疗,也未回来复诊。初次诊断两年后,她出现肠梗阻。恶性黑色素瘤已进展至晚期,出现肺、肝、腹膜和脊柱的多处转移。患者接受了转流性回肠造口术。手术时发现,肛管原发性恶性黑色素瘤已连续累及整个大肠直至回盲部,因此无法行横结肠造口术。