Buissin Dominique, Sterle Alenka, Schmiegelow Peter, Wassenberg Dirk, Ambe Peter C
Institute of Pathology, Städtliches Klinik Solingen, Gotenstraße 1, Solingen, Germany.
Department of General, Visceral and Thoracic Surgery, St. Remigius Hospital Opladen, An St. Remigius 26, 51379, Leverkusen, Germany.
World J Surg Oncol. 2015 Jan 30;13:12. doi: 10.1186/s12957-014-0419-z.
This report presents a case of primary anorectal melanoma. A 63-year-old male presented with blood in stool. Rectal digital examination and proctoscopy revealed a mass in the anorectal junction. Transanal polypectomy was performed. Histopathology and immunohistochemistry with Melan A showed a malignant anorectal melanoma with positive resection margins. Abdomino-perineal rectum resection was performed after excluding distant metastasis. Four month later, the patient was readmitted with metastases to the liver and to the gastric mucosa. Best supportive care was initiated. This case report demonstrates the aggressive nature of this rare tumor and appeals for a less aggressive management while maintaining the quality of life.
本报告介绍了一例原发性肛管直肠癌病例。一名63岁男性因便血就诊。直肠指检和直肠镜检查发现肛管直肠交界处有一肿物。遂行经肛门息肉切除术。组织病理学检查及Melan A免疫组化显示为恶性肛管直肠癌，切缘阳性。排除远处转移后，行腹会阴联合直肠癌根治术。四个月后，患者因肝转移和胃黏膜转移再次入院。开始给予最佳支持治疗。本病例报告显示了这种罕见肿瘤的侵袭性，并呼吁在维持生活质量的同时采取侵袭性较小的治疗方法。
