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Effects of Eupatilin on Insulin-Like Growth Factor 1-Induced Lipogenesis and Inflammation of SZ95 Sebocytes.

作者信息

Lee Ji Hyun, Lee Ye Jin, Song Ji Young, Kim Yeong Ho, Lee Jun Young, Zouboulis Christos C, Park Young Min

机构信息

Department of Dermatology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.

Department of Biomedicine & Health Sciences, College of Medicine, The Catholic University of Korea, Seoul, Korea.

出版信息

Ann Dermatol. 2019 Aug;31(4):479-482. doi: 10.5021/ad.2019.31.4.479. Epub 2019 Jul 1.

DOI:10.5021/ad.2019.31.4.479
PMID:33911635
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7992769/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fdcc/7992769/9fd0e1586271/ad-31-479-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fdcc/7992769/f4736e27184a/ad-31-479-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fdcc/7992769/9fd0e1586271/ad-31-479-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fdcc/7992769/f4736e27184a/ad-31-479-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fdcc/7992769/9fd0e1586271/ad-31-479-g002.jpg

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本文引用的文献

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Topical Application of Eupatilin Ameliorates Atopic Dermatitis-Like Skin Lesions in NC/Nga Mice.灯盏乙素的局部应用可改善NC/Nga小鼠的特应性皮炎样皮肤损伤。
Ann Dermatol. 2017 Feb;29(1):61-68. doi: 10.5021/ad.2017.29.1.61. Epub 2017 Feb 3.
2
Identification of Eupatilin from Artemisia argyi as a Selective PPARα Agonist Using Affinity Selection Ultrafiltration LC-MS.利用亲和选择超滤液相色谱-质谱联用技术从艾蒿中鉴定出灯盏乙素作为一种选择性过氧化物酶体增殖物激活受体α激动剂。
Molecules. 2015 Jul 28;20(8):13753-63. doi: 10.3390/molecules200813753.
3
Role of insulin, insulin-like growth factor-1, hyperglycaemic food and milk consumption in the pathogenesis of acne vulgaris.
胰岛素、胰岛素样生长因子-1、高血糖食物及牛奶摄入在寻常痤疮发病机制中的作用
Exp Dermatol. 2009 Oct;18(10):833-41. doi: 10.1111/j.1600-0625.2009.00924.x. Epub 2009 Aug 25.
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Eupatilin protects gastric epithelial cells from oxidative damage and down-regulates genes responsible for the cellular oxidative stress.灯盏乙素可保护胃上皮细胞免受氧化损伤,并下调负责细胞氧化应激的基因。
Pharm Res. 2008 Jun;25(6):1355-64. doi: 10.1007/s11095-008-9531-5.
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Inhibitory effect of eupatilin and jaceosidin isolated from Artemisia princeps in IgE-induced hypersensitivity.从白头翁中分离出的灯盏乙素和紫花前胡苷对IgE诱导的超敏反应的抑制作用。
Int Immunopharmacol. 2007 Dec 15;7(13):1678-84. doi: 10.1016/j.intimp.2007.08.028. Epub 2007 Sep 25.
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J Invest Dermatol. 2006 Sep;126(9):2002-9. doi: 10.1038/sj.jid.5700336. Epub 2006 May 4.
8
Acne and sebaceous gland function.痤疮与皮脂腺功能。
Clin Dermatol. 2004 Sep-Oct;22(5):360-6. doi: 10.1016/j.clindermatol.2004.03.004.
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Overexpression of Insig-1 in the livers of transgenic mice inhibits SREBP processing and reduces insulin-stimulated lipogenesis.Insig-1在转基因小鼠肝脏中的过表达会抑制固醇调节元件结合蛋白(SREBP)的加工,并减少胰岛素刺激的脂肪生成。
J Clin Invest. 2004 Apr;113(8):1168-75. doi: 10.1172/JCI20978.
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The biology of peroxisome proliferator-activated receptors: relationship with lipid metabolism and insulin sensitivity.过氧化物酶体增殖物激活受体的生物学:与脂质代谢和胰岛素敏感性的关系。
Diabetes. 2004 Feb;53 Suppl 1:S43-50. doi: 10.2337/diabetes.53.2007.s43.