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青年与老年胃癌患者的对比研究

Comparative study of gastric cancer in young and aged patients.

作者信息

Okamoto T, Makino M, Kawasumi H, Kimura O, Nishidoi H, Kaibara N, Koga S

机构信息

1st Department of Surgery, Tottori University School of Medicine, Yonago, Japan.

出版信息

Eur Surg Res. 1988;20(2):149-55. doi: 10.1159/000128754.

DOI:10.1159/000128754
PMID:3391235
Abstract

Clinical and pathological findings of gastric cancer in patients of less than 30 years of age were compared with those in aged patients of over 75 years of age. These were 10 males and 24 females, and the rate of gastric cancer for females in the younger group was extremely high. There were marked differences between both groups in the pathological findings of gastric cancer, and consequently in the progressive pattern of the disease, perhaps as the result of differences in the matrix of cancer development and the influence of sex hormones. Gastric cancer at an advanced stage and delayed surgery in younger patients are attributable to negligence on the part of the patient in scheduling a medical examination and careless diagnosis by the physician. However, the prognosis of gastric cancer was not unfavorable in the younger patients when curative surgery was performed.

摘要

将30岁以下胃癌患者的临床和病理结果与75岁以上老年患者的结果进行了比较。其中男性10例,女性24例,年轻组女性胃癌发病率极高。两组胃癌的病理结果存在显著差异,因此疾病的进展模式也有所不同,这可能是由于癌症发生基质的差异和性激素的影响。年轻患者中晚期胃癌和手术延迟归因于患者在安排体检时的疏忽以及医生的粗心诊断。然而,当进行根治性手术时,年轻患者胃癌的预后并不差。

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Br J Cancer. 1991 Jun;63(6):1015-7. doi: 10.1038/bjc.1991.220.