Maehara Y, Orita H, Moriguchi S, Emi Y, Haraguchi M, Sugimachi K
Department of Surgery II, Faculty of Medicine, Kyushu University, Fukuoka, Japan.
Br J Cancer. 1991 Jun;63(6):1015-7. doi: 10.1038/bjc.1991.220.
We analysed data on 38 patients with gastric cancer aged 30 years and younger who were surgically treated in the Department of Surgery II, Kyushu University Hospital, between 1965 to 1985. These younger patients comprised 2.6% of the total 1,470 patients treated for gastric cancer during this 21-year period. The durations and the kinds of symptoms in the preoperative period varied with the patient. In patients under 30 years of age, the female patients predominated, and in addition, undifferentiated lesions were more common than the differentiated type, tumours were larger, serosal invasion was more prominent, lymphatic involvement was more common, tumours showed infiltrative growth and the rate of peritoneal dissemination was higher. Consequently the survival rates for these younger patients were poor. Detection at an early stage of the disease is mandatory if the survival rates of younger patients with gastric cancer are to improve.
我们分析了1965年至1985年间在九州大学医院第二外科接受手术治疗的38例30岁及以下胃癌患者的数据。在这21年期间接受胃癌治疗的1470例患者中，这些年轻患者占2.6%。术前症状的持续时间和种类因人而异。在30岁以下的患者中，女性患者居多，此外，未分化病变比分化型更常见，肿瘤更大，浆膜侵犯更显著，淋巴结受累更常见，肿瘤呈浸润性生长，腹膜播散率更高。因此，这些年轻患者的生存率较低。如果要提高年轻胃癌患者的生存率，必须在疾病早期进行检测。
