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来自黄花稔属植物的次生代谢产物及其生物活性。

Secondary metabolite compounds from Sida genus and their bioactivity.

作者信息

Aminah N S, Laili E R, Rafi M, Rochman A, Insanu M, Tun K N W

机构信息

Department of Chemistry, Faculty of Science and Technology, Universitas Airlangga, Komplek Kampus C, Jl. Mulyorejo, Surabaya, 60115, Indonesia.

Department of Chemistry, Faculty of Mathematics and Natural Sciences, Institut Pertanian Bogor, Jalan Tanjung Kampus IPB Dramaga, Bogor 16680, Indonesia.

出版信息

Heliyon. 2021 Apr 10;7(4):e06682. doi: 10.1016/j.heliyon.2021.e06682. eCollection 2021 Apr.

Abstract

Plants are the key source for the production of novel therapeutic products for new medicines. The biological properties of the plant species used world wide are mainly accountable for their secondary metabolites obtained from plants. The goal of this analysis is to summarize the chemical composition and biological effects of the genus Sida (Malvaceae) to identify potential research opportunities. This analysis draws on the literature review of scientific journals, and books from libraries, and electronic sources like ScienceDirect, Springer, PubMed, ResearchGate, Google Scholar, and the Website. Some groups of secondary metabolite compounds isolated from the genus Sida include alkaloids, flavonoids, coumarin, and others. Pharmacological experiments found that there are a wide variety of biological activities in extracts and compounds isolated from the genus Sida comprising antimalarial, antiplasmodial, antimicrobial, analgesic, antibacterial, antioxidant, vasorelaxant, wound healing, antifungal activities, the inhibition of quinone reductase, and mouse mammary organ culture.

摘要

植物是新型药物治疗产品生产的关键来源。全球使用的植物物种的生物学特性主要归因于从植物中获得的次生代谢产物。本分析的目的是总结 sida 属(锦葵科)的化学成分和生物学效应,以确定潜在的研究机会。本分析借鉴了科学期刊的文献综述、图书馆的书籍以及 ScienceDirect、Springer、PubMed、ResearchGate、Google Scholar 和该网站等电子资源。从 sida 属中分离出的一些次生代谢化合物组包括生物碱、黄酮类化合物、香豆素等。药理实验发现,从 sida 属中分离出的提取物和化合物具有多种生物活性,包括抗疟疾、抗疟原虫、抗菌、止痛、抗菌、抗氧化、血管舒张、伤口愈合、抗真菌活性、醌还原酶抑制以及小鼠乳腺器官培养。

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