Alshehri Abdulaziz M
Ophthalmology, Taif University, Taif, SAU.
Cureus. 2024 Sep 30;16(9):e70523. doi: 10.7759/cureus.70523. eCollection 2024 Sep.
Endogenous endophthalmitis (EE) is a rare but severe intraocular infection resulting from hematogenous dissemination of microorganisms. During the COVID-19 pandemic, there has been a notable increase in EE cases. This literature review aims to evaluate studies focusing on EE associated with COVID-19 to elucidate its pathogenesis and optimize patient management strategies. A thorough search was conducted across PubMed, ScienceDirect, and Google Scholar for relevant research. The surge in EE cases during the COVID-19 pandemic is likely linked to alterations in immune status and systemic comorbidities exacerbated by the virus and its treatments. Notably, and species emerged as the predominant fungal pathogens in these cases. The findings suggest that the increased incidence of EE is associated with immune dysregulation and increased vulnerability of COVID-19 patients, particularly those with severe diseases or undergoing immunosuppressive treatments. Early diagnosis with timely and effective treatment is crucial for improving patient outcomes. Regular ophthalmic evaluations for hospitalized COVID-19 patients are strongly advised to detect and address ocular complications early.
内源性眼内炎（EE）是一种罕见但严重的眼内感染，由微生物的血行播散引起。在新冠疫情期间，EE病例显著增加。这篇文献综述旨在评估聚焦于与新冠相关的EE的研究，以阐明其发病机制并优化患者管理策略。我们在PubMed、ScienceDirect和谷歌学术上全面检索了相关研究。新冠疫情期间EE病例的激增可能与免疫状态的改变以及病毒及其治疗加剧的全身性合并症有关。值得注意的是，在这些病例中，[具体真菌名称1]和[具体真菌名称2]成为主要的真菌病原体。研究结果表明，EE发病率的增加与免疫失调以及新冠患者，尤其是重症患者或接受免疫抑制治疗的患者的易感性增加有关。早期诊断并及时进行有效治疗对于改善患者预后至关重要。强烈建议对住院的新冠患者进行定期眼科评估，以便早期发现并处理眼部并发症。
