Central de Análises de Fármacos, Medicamentos E Alimentos, Universidade Federal do Vale do São Francisco, Petrolina-PE, Brasil.
Faculdade Irecê, Irecê-BA, Brasil.
Expert Opin Ther Pat. 2021 Oct;31(10):937-949. doi: 10.1080/13543776.2021.1924149. Epub 2021 May 19.
: Metal organic frameworks (MOFs) are a recent group of nano porous materials with exceptional physical properties, such as large surface areas, high pore volumes, low densities and well-defined pores. This type of material has been used frequently for biomedical and therapeutic applications, such as drug delivery systems and theranostic materials.: In this review, the authors searched for patents filed in the last 10 years, found in different databases, related to the therapeutic or biomedical application of MOFs for use in different health fields. The possibility of these new materials becoming new therapeutic possibilities available to the population was emphasized.: The advances in research with MOFs have grown in the last 10 years and with that many possibilities for their applications have emerged in several areas, especially biomedical. The possibility of using these materials in drug delivery systems is the most common form of possibility of use in the health area, mainly due to easy obtaining and high reproducibility, which are seen very positively by the drug development technology sector.
金属有机骨架（MOFs）是一类新兴的纳米多孔材料，具有独特的物理性质，如大的比表面积、高的孔体积、低的密度和定义明确的孔。这种材料经常被用于生物医学和治疗应用，如药物传递系统和治疗诊断材料。
在这篇综述中，作者搜索了过去 10 年中在不同数据库中提交的专利，这些专利涉及 MOFs 在不同健康领域的治疗或生物医学应用。强调了这些新材料成为可供民众使用的新治疗可能性的可能性。
在过去的 10 年中，MOFs 的研究进展迅速，因此在许多领域出现了许多应用的可能性，特别是在生物医学领域。在药物传递系统中使用这些材料的可能性是在健康领域最常见的使用形式，主要是因为它们易于获得和具有高重现性，这受到药物开发技术领域的高度评价。
