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针刺对绝经后高血压前期或1级高血压女性降压作用的倾向评分匹配分析

Effects of Acupuncture on Lowering Blood Pressure in Postmenopausal Women with Prehypertension or Stage 1 Hypertension: A Propensity Score-Matched Analysis.

作者信息

Seo Bok-Nam, Kwon Ojin, Lee Siwoo, Kim Ho-Seok, Kang Kyung-Won, Seol In Chan, Shin Chol, Choi Sun-Mi

机构信息

Clinical Medicine Division, Korea Institute of Oriental Medicine, Daejeon 34054, Korea.

Future Medicine Division, Korea Institute of Oriental Medicine, Daejeon 34054, Korea.

出版信息

J Clin Med. 2021 Apr 1;10(7):1426. doi: 10.3390/jcm10071426.

Abstract

Postmenopausal women have a higher prevalence of hypertension compared to premenopausal women. Hypertension is a risk factor for cardiovascular diseases, the prevalence of which is ever increasing. This study investigated the effects of long-term acupuncture on lowering the blood pressure of postmenopausal women with prehypertension and stage 1 hypertension. Participants were 122 postmenopausal women aged less than 65 years, diagnosed with prehypertension or stage 1 hypertension (systolic blood pressure 120-159 mmHg or diastolic blood pressure 80-99 mmHg). We used a propensity score-matched design. The experimental group ( = 61) received acupuncture for four weeks every six months over a period of two years. The control group ( = 61) received no intervention. An Analysis of covariance (ANCOVA) was performed for the primary efficacy analysis. Relative risk ratios were used to compare group differences in treatment effects. Acupuncture significantly reduced the participants' diastolic blood pressure (-9.92 mmHg; < 0.001) and systolic blood pressure (-10.34 mmHg; < 0.001) from baseline to follow-up. The results indicate that acupuncture alleviates hypertension in postmenopausal women, reducing their risk of developing cardiovascular diseases and improving their health and quality of life.

摘要

与绝经前女性相比,绝经后女性高血压的患病率更高。高血压是心血管疾病的一个危险因素,其患病率正在不断上升。本研究调查了长期针灸对降低绝经后高血压前期和1期高血压女性血压的影响。研究对象为122名年龄小于65岁、诊断为高血压前期或1期高血压(收缩压120 - 159 mmHg或舒张压80 - 99 mmHg)的绝经后女性。我们采用了倾向得分匹配设计。实验组(n = 61)在两年的时间里每六个月接受四周的针灸治疗。对照组(n = 61)不接受任何干预。采用协方差分析(ANCOVA)进行主要疗效分析。使用相对风险比来比较组间治疗效果的差异。从基线到随访,针灸显著降低了参与者的舒张压(-9.92 mmHg;P < 0.001)和收缩压(-10.34 mmHg;P < 0.001)。结果表明,针灸可缓解绝经后女性的高血压,降低其患心血管疾病的风险,并改善她们的健康状况和生活质量。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/50ed/8038045/d507f7d5c407/jcm-10-01426-g001.jpg

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