中氮茚及其杂环/苯并衍生物在[8 + 2]环加成反应中的应用
Indolizines and Their Hetero/Benzo Derivatives in Reactions of [8+2] Cycloaddition.
作者信息
Babaev Eugene V, Shadrin Ivan A
机构信息
Chemistry Department, Moscow State University, Leninskie Gory, 1 Str. 3, 119899 Moscow, Russia.
Higher School of Economics, National Research University, 7 Vavilova Str., 117312 Moscow, Russia.
出版信息
Molecules. 2021 Apr 3;26(7):2050. doi: 10.3390/molecules26072050.
Peculiarities of [8+2] cycloaddition of acetylenes to indolizines are reviewed. Especially mentioned are indolizines with leaving groups at positions 3 and 5. Cycloaddition to aza- and benzo derivatives are reviewed, as well as 1,10-cyclizations and processes leading to cyclazines where indolizines are intermediates. Mechanistic features (adducts and cycloadducts) and theoretical aspects (one- or two-steps mechanism) are reviewed.
综述了乙炔与中氮茚的[8 + 2]环加成反应的特点。特别提到了在3位和5位带有离去基团的中氮茚。综述了与氮杂和苯并衍生物的环加成反应，以及1,10-环化反应和以中氮茚为中间体生成环嗪的反应过程。综述了机理特征（加合物和环加合物）和理论方面（一步或两步机理）。
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