Center for Human Nutrition, Department of International Health, The Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA.
Department of Maternal and Child Health, Peking University School of Public Health, Beijing 100191, China.
Nutrients. 2021 Apr 3;13(4):1188. doi: 10.3390/nu13041188.
Findings on the role of Mediterranean-style diet (MSD) on duration of pregnancy and birth weight have been inconsistent and based largely on Non-Hispanic white populations, making it unclear as to whether they could extend to African Americans who are at a higher risk of unfavorable birth outcomes. Our study addresses this gap using a large urban, multiethnic, predominantly low-income cohort of mother-infant dyads from Boston, MA, USA. Dietary information was obtained via food frequency questionnaires; health information including birth outcomes were extracted from medical records. A Mediterranean-style diet score (MSDS) was formulated based on intake history, and linear and log-binomial regressions were performed to assess its association with birth outcomes. After adjustment, the lowest MSDS quintile from the overall sample was found to be associated with an increased relative risk (RR) of overall preterm birth (RR 1.18; 95% CI: 1.06-1.31), spontaneous preterm birth (1.28; 1.11-1.49), late preterm birth (1.21; 1.05-1.39), and low birth weight (1.11; 1.01-1.22), compared to the highest quintile. The findings were similar for the African American sample. Our study adds to the current understanding of the diet's influence on birth outcomes by demonstrating that adherence to MSD may improve birth outcomes for African American women.
关于地中海式饮食(MSD)对孕期和出生体重的作用的研究结果一直不一致,并且主要基于非西班牙裔白人群体,因此不清楚它们是否适用于出生结局较差风险较高的非裔美国人。我们的研究使用了来自美国马萨诸塞州波士顿的一个大型城市、多种族、以低收入为主的母婴对队列,解决了这一差距。通过食物频率问卷获取饮食信息;从病历中提取健康信息,包括出生结果。根据摄入史制定了地中海式饮食评分(MSDS),并进行了线性和对数二项式回归分析,以评估其与出生结果的关联。调整后,从整个样本中最低的 MSDS 五分位数被发现与总早产(RR 1.18;95%CI:1.06-1.31)、自发性早产(1.28;1.11-1.49)、晚期早产(1.21;1.05-1.39)和低出生体重(1.11;1.01-1.22)的相对风险增加有关,与最高五分位数相比。在非裔美国人样本中也发现了类似的结果。我们的研究通过证明坚持 MSD 可能改善非裔美国女性的出生结局,为饮食对出生结局的影响增加了新的认识。