3-芳亚基-3-吲哚鎓盐、异氰化物和胺的三组分反应。
Three-Component Reactions of 3-Arylidene-3-Indolium Salts, Isocyanides and Amines.
机构信息
Department of Organic Chemistry, Faculty of Science, Peoples' Friendship University of Russia (RUDN University), 6 Miklukho-Maklaya St., 117198 Moscow, Russia.
Faculty of Natural Sciences, Hung Vuong University, Nguyen Tat Thanh Street, Viet Tri 35120, Vietnam.
出版信息
Molecules. 2021 Apr 21;26(9):2402. doi: 10.3390/molecules26092402.
Abstract
A multicomponent reaction of isocyanides with aryl(indol-3-yl)methylium salts and amines has been found. A series of aryl(indol-3-yl)acetimidamides was obtained in up to 96% yields. In the case of ethyl isocyanoacetate, the reaction is followed by cyclization to form 3,5-dihydro-4-imidazol-4-one derivatives.
摘要
已发现异氰化物与芳基（吲哚-3-基）甲鎓盐和胺的多组分反应。以高达 96%的收率获得了一系列芳基（吲哚-3-基）乙酰胺。在乙基异氰基乙酸酯的情况下，反应随后进行环化以形成 3,5-二氢-4-咪唑-4-酮衍生物。
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