Drop L J, Bouckoms A J, Welch C A
Department of Anesthesia, Massachusetts General Hospital, Boston 02114.
J Clin Psychiatry. 1988 Jul;49(7):280-2.
The authors successfully instituted two courses of ECT at a 1-year interval for drug-resistant major depression in a patient with arterial hypertension and intracranial aneurysms. Both ECT courses required arterial and central venous cannulas, but the first course was complicated by an unusual and excessive degree of hypertension, which was not appropriately responsive to high doses of sodium nitroprusside (9 micrograms/kg/minute). Appropriate responsiveness to nitroprusside was established after therapy with timolol. The combination of sodium nitroprusside and timolol proved effective throughout the second course of ECT.
作者成功地为一名患有动脉高血压和颅内动脉瘤的耐药性重度抑郁症患者，每隔1年进行了两个疗程的ECT治疗。两个ECT疗程均需要动脉和中心静脉插管，但第一个疗程出现了异常且过度的高血压并发症，对高剂量硝普钠（9微克/千克/分钟）反应不佳。在用噻吗洛尔治疗后，对硝普钠产生了适当反应。在ECT的第二个疗程中，硝普钠和噻吗洛尔的联合用药被证明是有效的。
