Joung Kyoung-Woon, Park Dong Ho, Jeong Chang Young, Yang Hong Seuk
Department of Anesthesiology and Pain Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Department of Anesthesiology and Pain Medicine, Daejeon Eulji Medical Center, Eulji University School of Medicine, Daejeon, Korea.
Anesth Pain Med (Seoul). 2022 Apr;17(2):145-156. doi: 10.17085/apm.22145. Epub 2022 Apr 15.
Counselling and medication are often thought of as the only interventions for psychiatric disorders, but electroconvulsive therapy (ECT) has also been applied in clinical practice for over 80 years. ECT refers to the application of an electric stimulus through the patient's scalp to treat psychiatric disorders such as treatment-resistant depression, catatonia, and schizophrenia. It is a safe, effective, and evidence-based therapy performed under general anesthesia with muscle relaxation. An appropriate level of anesthesia is essential for safe and successful ECT; however, little is known about this because of the limited interest from anesthesiologists. As the incidence of ECT increases, more anesthesiologists will be required to better understand the physiological changes, complications, and pharmacological actions of anesthetics and adjuvant drugs. Therefore, this review focuses on the fundamental physiological changes, management, and pharmacological actions associated with various drugs, such as anesthetics and neuromuscular blocking agents, as well as the comorbidities, indications, contraindications, and complications of using these agents as part of an ECT procedure through a literature review and our own experiences.
咨询和药物治疗常常被认为是精神疾病的唯一干预措施,但电休克疗法(ECT)在临床实践中的应用也已超过80年。ECT是指通过患者头皮施加电刺激来治疗难治性抑郁症、紧张症和精神分裂症等精神疾病。它是一种在全身麻醉和肌肉松弛状态下进行的安全、有效且基于证据的治疗方法。适当的麻醉水平对于安全且成功地进行ECT至关重要;然而,由于麻醉医生兴趣有限,对此了解甚少。随着ECT发病率的增加,将需要更多麻醉医生来更好地理解麻醉药和辅助药物的生理变化、并发症及药理作用。因此,本综述通过文献回顾和我们自己的经验,重点关注与各种药物(如麻醉药和神经肌肉阻滞剂)相关的基本生理变化、管理及药理作用,以及将这些药物用作ECT程序一部分时的合并症、适应症、禁忌症和并发症。