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一名接受血液透析的肾衰竭儿科患者中与新型冠状病毒肺炎相关的心肌心包炎

Myopericarditis Associated with COVID-19 in a Pediatric Patient with Kidney Failure Receiving Hemodialysis.

作者信息

Ionescu Marcela Daniela, Balgradean Mihaela, Cirstoveanu Catalin Gabriel, Balgradean Ioana, Popa Loredana Ionela, Pavelescu Carmen, Capitanescu Andrei, Berghea Elena Camelia, Filip Cristina

机构信息

Department of Pediatrics, "Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania.

"Maria Sklodowska Curie" Emergency Children's Hospital, 041451 Bucharest, Romania.

出版信息

Pathogens. 2021 Apr 17;10(4):486. doi: 10.3390/pathogens10040486.

DOI:10.3390/pathogens10040486
PMID:33920512
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8073656/
Abstract

The outbreak of COVID-19 can be associated with cardiac and pulmonary involvement and is emerging as one of the most significant and life-threatening complications in patients with kidney failure receiving hemodialysis. Here, we report a critically ill case of a 13-year-old female patient with acute pericarditis and bilateral pleurisy, screened positive for SARS-CoV-2 RT-PCR, presented with high fever, frequent dry cough, and dyspnea with tachypnea. COVID-19-induced myopericarditis has been noted to be a complication in patients with concomitant kidney failure with replacement therapy (KFRT). This article brings information in the light of our case experience, suggesting that the direct effect of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection on cardiac tissue was a significant contributor to myopericarditis in our patient. Further studies in this direction are required, as such associations have thus far been reported.

摘要

新型冠状病毒肺炎(COVID-19)的爆发可能与心脏和肺部受累有关,并且正成为接受血液透析的肾衰竭患者中最严重且危及生命的并发症之一。在此,我们报告一例危重症病例,一名13岁女性患者,患有急性心包炎和双侧胸膜炎,严重急性呼吸综合征冠状病毒2(SARS-CoV-2)逆转录聚合酶链反应(RT-PCR)检测呈阳性,表现为高热、频繁干咳以及伴有呼吸急促的呼吸困难。COVID-19诱发的心肌心包炎已被认为是接受替代治疗的合并肾衰竭(KFRT)患者的一种并发症。本文根据我们的病例经验提供信息,表明严重急性呼吸综合征冠状病毒2(SARS-CoV-2)感染对心脏组织的直接影响是导致我们患者发生心肌心包炎的一个重要因素。鉴于迄今为止已有此类关联的报道,因此需要在这个方向上进行进一步研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/387a/8073656/d14fc8f2aaad/pathogens-10-00486-g008.jpg
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