Saito Gustavo Pereira, Matsumoto Ana Carolina Lanfredi, Assis Renata Pires, Brunetti Iguatemy Lourenço, Cebim Marco Aurélio, Davolos Marian Rosaly
Institute of Chemistry, São Paulo State University (Unesp), Araraquara 14800-060, São Paulo, Brazil.
School of Pharmaceutical Sciences, São Paulo State University (Unesp), Araraquara 14800-903, São Paulo, Brazil.
Molecules. 2021 Apr 17;26(8):2349. doi: 10.3390/molecules26082349.
Excessive UV solar radiation exposure causes human health risks; therefore, the study of multifunctional filters is important to skin UV protective ability and also to other beneficial activities to the human organism, such as reduction of reactive oxygen species (ROS) responsible for cellular damages. Potential multifunctional filters were obtained by intercalating of ferulate anions into layered simple metal hydroxides (LSH) through anion exchange and precipitation at constant pH methods. Ultrasound treatment was used in order to investigate the structural changes in LSH-ferulate materials. Structural and spectroscopic analyses show the formation of layered materials composed by a mixture of LSH intercalated with ferulate anions, where carboxylate groups of ferulate species interact with LSH layers. UV-VIS absorption spectra and SPF measurements indicate that LSH-ferulate systems have UV shielding capacity, mainly UVB protection. The results of reactive species assays show the ability of layered compounds in capture DPPH, ABTS, ROO, and HOCl/OCl reactive species. LSH-ferulate materials exhibit antioxidant activity and singular optical properties that enable their use as multifunctional filters.
过度暴露于太阳紫外线辐射会对人类健康构成风险；因此，研究多功能滤光片对于皮肤的紫外线防护能力以及对人体机体的其他有益活动，如减少导致细胞损伤的活性氧（ROS）而言至关重要。通过在恒定pH值下采用阴离子交换和沉淀法将阿魏酸根阴离子插入层状单金属氢氧化物（LSH）中，获得了潜在的多功能滤光片。为了研究LSH - 阿魏酸材料的结构变化，采用了超声处理。结构和光谱分析表明，形成了由插入阿魏酸根阴离子的LSH混合物组成的层状材料，其中阿魏酸物种的羧酸根基团与LSH层相互作用。紫外 - 可见吸收光谱和防晒系数（SPF）测量表明，LSH - 阿魏酸体系具有紫外线屏蔽能力，主要是对中波紫外线（UVB）的防护。活性物种测定结果表明，层状化合物具有捕获二苯基苦味酰基自由基（DPPH）、2,2'-联氮-双-3-乙基苯并噻唑啉-6-磺酸（ABTS）、过氧自由基（ROO）和次氯酸/次氯酸根（HOCl/OCl）活性物种的能力。LSH - 阿魏酸材料表现出抗氧化活性和独特的光学性质，使其能够用作多功能滤光片。
